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1-o-Hexadecyl-2-Butyryl-Sn-Glycero-3-Phosphocholine CAS NO 85405-03-4


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CAS No.:85405-03-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1-o-Hexadecyl-2-Butyryl-Sn-Glycero-3-Phosphocholine is a synthetic, high-purity phospholipid derivative, specifically a lysophosphatidylcholine (LPC) analog with defined acyl chain substitution. This compound is of significant value for its role as a critical biochemical tool and a potential precursor in advanced formulation science. It is primarily needed by researchers and manufacturers in the life sciences, pharmaceutical development, and specialty chemical sectors for applications requiring precise lipid membrane interaction and modification.

Application

  • Biochemical Research & Standard: Used as a reference standard in lipidomics, metabolomics, and analytical method development for accurate quantification of lysophospholipids.
  • Lipid Nanoparticle (LNP) Formulation: Serves as a functional excipient or structural component in the development of advanced drug delivery systems for nucleic acids (mRNA, siRNA).
  • Cell Membrane Studies: Employed in biophysical research to study lipid bilayer properties, membrane fluidity, and the behavior of lipid rafts.
  • Pharmaceutical Intermediates: Acts as a key synthetic intermediate for the production of more complex, therapeutic phospholipids and prodrugs.
  • Signal Transduction Research: Investigated for its role and effects in cellular signaling pathways mediated by lysophosphatidylcholine and related bioactive lipids.
  • Cosmetic & Dermal Formulations: Utilized in high-end cosmetic products for its emulsifying properties and potential skin barrier interaction.

Basic Information

Item Detail
Product Name 1-o-Hexadecyl-2-Butyryl-Sn-Glycero-3-Phosphocholine
CAS No. 85405-03-4
Molecular Formula C₂₈H₅₈NO₇P
Molecular Weight 551.74 g/mol
Synonyms 1-Hexadecyl-2-butyryl-sn-glycero-3-phosphocholine; C16:0/4:0 LPC; LysoPC(16:0/4:0); 1-Palmitoyl-2-butyroyl-sn-glycero-3-phosphocholine; 2-Butyroyl-1-hexadecyl-sn-glycero-3-phosphocholine; LPC 16:0/4:0; 1-O-Hexadecyl-2-butyroyl-sn-glycero-3-phosphorylcholine; sn-Glycero-3-phosphocholine, 1-hexadecyl-2-butyryl ester
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Quality Control

Our 1-o-Hexadecyl-2-Butyryl-Sn-Glycero-3-Phosphocholine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (NMR, MS), to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation. For long-term storage, keep under an inert atmosphere.

Specification

Item Specification
Appearance White to off-white solid or waxy solid
Identification (HPLC/MS) Conforms to reference standard
Purity (HPLC) ≥ 95% (Area %)
Assay (Titration) ≥ 98.0%
Water Content (KF) ≤ 1.0%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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