Description

1-Palmitoyl-2-(4-Doxylpentanoyl)Glycerophosphocholine is a specialized, spin-labeled phospholipid derivative used as a critical molecular probe in biophysical research. Its core value lies in enabling the study of membrane dynamics, structure, and lipid-protein interactions through advanced techniques like Electron Paramagnetic Resonance (EPR) spectroscopy. This compound is essential for researchers and developers in the pharmaceutical, biotechnology, and life sciences sectors who require precise tools for investigating cell membrane behavior and drug delivery mechanisms.

Application

• Membrane Biophysics Research: As a spin-label probe for Electron Paramagnetic Resonance (EPR) spectroscopy to study lipid bilayer dynamics, fluidity, and phase transitions.
• Lipid-Protein Interaction Studies: To investigate the binding and conformational changes of membrane-associated proteins and peptides within model lipid membranes.
• Drug Delivery System Development: Used in the formulation and characterization of liposomal and other lipid-based nanocarriers to understand stability and release kinetics.
• Model Membrane Systems: A key component in creating defined liposomes and supported lipid bilayers (SLBs) for in vitro assays and sensor development.
• Oxidative Stress Studies: Employed to monitor and quantify free radical generation and lipid peroxidation processes in biological membranes.
• Academic & Industrial R&D: A vital tool in biochemistry and molecular biology laboratories for fundamental and applied research into membrane structure and function.

Basic Information

Product Name	1-Palmitoyl-2-(4-Doxylpentanoyl)Glycerophosphocholine
CAS No.	85284-79-3
Molecular Formula	C₃₀H₅₇N₂O₈P
Molecular Weight	604.76 g/mol
Synonyms	16:0-5-Doxyl PC; 1-Palmitoyl-2-stearoyl-(5-doxyl)-sn-glycero-3-phosphocholine; 5-Doxyl PC; 5-DOXYL-PC; Phosphatidylcholine, 1-palmitoyl-2-(4-doxylpentanoyl)-; 1-Palmitoyl-2-(5-doxylpentanoyl)-sn-glycero-3-phosphocholine; 5-Doxylphosphatidylcholine; Spin-labeled phosphatidylcholine
EINECS	Contact for details

Quality Control

Our 1-Palmitoyl-2-(4-Doxylpentanoyl)Glycerophosphocholine is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for research-grade biochemicals, ensuring reliable performance in your experimental systems.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation. For long-term storage, desiccate at -80°C. Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	Yellow to orange waxy solid or film
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Assay (EPR)	Active spin label confirmed
Solubility	Soluble in chloroform, ethanol; forms liposomes in aqueous buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.