Description

17(S)-Tipredane is a high-purity synthetic corticosteroid derivative, identified by CAS NO 85197-76-8. This compound is a critical intermediate in the pharmaceutical synthesis of potent anti-inflammatory agents, offering significant value for research and development of novel therapeutics. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions focused on steroid chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of advanced corticosteroid drugs and prodrugs.
• Anti-inflammatory Research: Used as a reference standard and active compound in preclinical studies investigating glucocorticoid receptor activity.
• Process Chemistry: Serves as a crucial intermediate in the scale-up and optimization of steroid-based API manufacturing processes.
• Analytical Standard: Provides a high-purity standard for method development and quality control (HPLC, GC, MS) in analytical laboratories.
• Biochemical Research: Employed in studies to understand steroid metabolism, receptor binding affinity, and structure-activity relationships (SAR).

Basic Information

Product Name	17(S)-Tipredane
CAS No.	85197-76-8
Molecular Formula	C24H31FO5S
Molecular Weight	450.56 g/mol
Synonyms	Tipredane (17S-isomer); 9-Fluoro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione 21-(ethylthio)-17α-propionate; SQ-27239; (17S)-9-Fluoro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione 21-(ethylthio)-17α-propionate; 17α-[(Ethylthio)carbonyl]-9-fluoro-11β-hydroxy-16β-methyl-3-oxoandrosta-1,4-diene-17β-carbothioic acid S-propyl ester
EINECS	Contact for details

Quality Control

Our 17(S)-Tipredane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis, to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccant or inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.