Description

Dansyl Alprenolol is a fluorescent-labeled derivative of the β-blocker alprenolol, synthesized by conjugating it with dansyl chloride. This compound is primarily valued as a critical analytical standard and a fluorescent probe in biochemical and pharmacological research. It is essential for scientists and quality control laboratories in the pharmaceutical and life sciences sectors who require high-purity reference materials for method development, validation, and tracer studies.

Application

• Analytical Reference Standard: Used as a primary standard in HPLC, LC-MS, and other chromatographic methods for the quantification of alprenolol and related compounds.
• Biochemical Research: Serves as a fluorescent probe for studying β-adrenergic receptor binding, localization, and dynamics due to its specific affinity and fluorescent properties.
• Pharmaceutical Development: Employed in the development and validation of analytical methods for drug substance and product testing during R&D and quality control.
• Metabolic Studies: Utilized as a tracer in in vitro and in vivo studies to investigate the metabolism and pharmacokinetics of β-blockers.
• Diagnostic Assay Development: Acts as a key component in developing fluorescent immunoassays or other diagnostic tests for cardiovascular drug monitoring.

Basic Information

Product Name	Dansyl Alprenolol
CAS No.	85187-55-9
Molecular Formula	C28H35N3O3S
Molecular Weight	493.66 g/mol
Synonyms	5-(Dimethylamino)naphthalene-1-sulfonamide, N-[3-(2-cyclopropylphenoxy)-2-hydroxypropyl]-N-methyl-; Dansyl-Alprenolol; Alprenolol Dansyl Derivative; 1-[[2-(2-Cyclopropylphenoxy)-1-methylethyl]amino]-3-(1-naphthalenesulfonamido)-2-propanol; N-{1-[[2-(2-Cyclopropylphenoxy)-1-methylethyl]amino]-3-hydroxy-2-propyl}-N-methyl-5-(dimethylamino)-1-naphthalenesulfonamide
EINECS	Contact for details

Quality Control

Our Dansyl Alprenolol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and analytical applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to orange powder or crystalline solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (IR)	Spectrum matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.