Description

3-Iodocholic Acid is a halogenated derivative of the primary bile acid, cholic acid, where an iodine atom is introduced at the 3-position of the steroid nucleus. This specific modification makes it a valuable intermediate and reference standard in the synthesis of novel bile acid analogs and for metabolic pathway studies. It is primarily utilized by research institutions and pharmaceutical companies engaged in hepatobiliary research, drug discovery, and the development of diagnostic agents. The compound is supplied with a focus on high purity and batch-to-batch consistency to meet rigorous research and development requirements.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel bile acid receptor modulators and targeted therapeutics.
• Metabolic Research: Used as a tracer or standard in studying bile acid metabolism, transport, and related disorders.
• Biochemical Tool: Employed in enzyme inhibition studies and as a ligand for probing protein binding sites.
• Diagnostic Agent Development: Serves as a precursor for developing radiolabeled (e.g., with I-125 or I-131) compounds for imaging and diagnostic applications.
• Reference Standard: Provides a high-purity benchmark for analytical method development and quality control in related chemical production.

Basic Information

Product Name	3-Iodocholic Acid
CAS No.	85121-73-9
Molecular Formula	C24H39IO5
Molecular Weight	534.48 g/mol
Synonyms	3α,7α,12α-Trihydroxy-3-iodo-5β-cholan-24-oic Acid; 3-Iodo-5β-cholan-24-oic Acid-3α,7α,12α-triol; Iodocholic Acid; 3-Iodocholate; 3-Iodo-cholic Acid
EINECS	Contact for details

Quality Control

Our 3-Iodocholic Acid is produced and tested under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing specific batch results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 2.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.