Description

20Beta-Cortol-3-Glucuronide is a specific glucuronide conjugate of the steroid metabolite 20β-cortol, identified by CAS NO 85071-10-9. This compound is a critical reference standard and analytical tool for research in steroid metabolism and endocrinology. It is primarily required by pharmaceutical R&D laboratories, clinical diagnostic manufacturers, and academic institutions conducting advanced biochemical studies.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of steroid hormone metabolites in drug development and bioequivalence studies.
• Clinical Diagnostics: Serves as a calibrator or control in LC-MS/MS and HPLC assays for profiling endogenous steroids in patient samples.
• Metabolic Pathway Research: Essential for investigating phase II conjugation pathways, specifically glucuronidation, in steroid hormone catabolism.
• Enzyme Activity Studies: Employed as a substrate to study the activity and kinetics of UDP-glucuronosyltransferase (UGT) enzymes.
• Biomarker Development: Aids in the discovery and validation of steroid glucuronides as potential biomarkers for endocrine disorders.
• Quality Control: Used by manufacturers of in-vitro diagnostic (IVD) kits to ensure assay accuracy and reproducibility.

Basic Information

Product Name	20Beta-Cortol-3-Glucuronide
CAS No.	85071-10-9
Molecular Formula	C₂₇H₄₄O₉
Molecular Weight	524.64 g/mol
Synonyms	20β-Cortol 3-Glucuronide; 20β-Cortol 3-β-D-Glucopyranosiduronic Acid; (3β,5β,11β,20R)-3-(β-D-Glucopyranosiduronic acid)-11,17,20,21-tetrahydroxypregnan-18-al; 20β-Hydroxycortisol 3-Glucuronide; 20β-Dihydrocortisol 3-Glucuronide; Cortol 20β-Glucuronide; 20β-Cortol Glucuronide
EINECS	Contact for details

Quality Control

Our 20Beta-Cortol-3-Glucuronide is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and diagnostic applications. A detailed Certificate of Analysis (COA) with batch-specific data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in methanol, DMSO; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.