Description

(R)-2-((tert-Butoxycarbonyl)Amino)Propyl 4-Methylbenzenesulfonate is a high-purity chiral building block and pharmaceutical intermediate, essential for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs). Its value lies in providing a protected amine handle and a good leaving group, enabling precise stereochemical control in complex organic syntheses. This compound is critically needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing novel therapeutics and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the production of enantiomerically pure drugs, particularly in antiviral, anticancer, and central nervous system (CNS) therapeutic areas.
• Peptide Chemistry: Used in the synthesis of modified peptides and peptidomimetics where the (R)-configured amino alcohol moiety is required.
• Asymmetric Synthesis: Serves as a precursor for chiral ligands, catalysts, and auxiliaries used in stereoselective transformations.
• Agrochemical Research: Building block for the development of chiral pesticides and herbicides with improved efficacy and environmental profiles.
• Protecting Group Chemistry: The tert-butoxycarbonyl (Boc) group provides a base-labile protecting strategy for amines in multi-step syntheses.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological mechanisms and target engagement.

Basic Information

Product Name	(R)-2-((tert-Butoxycarbonyl)Amino)Propyl 4-Methylbenzenesulfonate
CAS No.	84765-24-2
Molecular Formula	C16H25NO5S
Molecular Weight	343.44 g/mol
Synonyms	(R)-2-((Boc)Amino)Propyl Tosylate; (R)-N-Boc-2-Aminopropyl Tosylate; (R)-1-[[(1,1-Dimethylethoxy)carbonyl]amino]-2-propanol 4-methylbenzenesulfonate; (R)-2-(Boc-amino)propyl p-toluenesulfonate; (R)-Boc-2-aminopropyl tosylate; (R)-2-(tert-Butoxycarbonylamino)propyl tosylate; (R)-N-(tert-Butoxycarbonyl)-2-aminopropyl 4-methylbenzenesulfonate; (R)-2-(Boc-amino)-1-propanol tosylate
EINECS	Contact for details

Quality Control

Our (R)-2-((tert-Butoxycarbonyl)Amino)Propyl 4-Methylbenzenesulfonate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including chiral purity verification by HPLC, to meet the stringent requirements of pharmaceutical R&D and cGMP intermediate production. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.