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1-o-Hexadecyl-2-Hexadecanoyl-Rac-Glycero-3-Phosphocholine CAS NO 84743-00-0
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CAS No.:84743-00-0
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
1-o-Hexadecyl-2-Hexadecanoyl-Rac-Glycero-3-Phosphocholine is a synthetic phospholipid analog, specifically a rac-glycerol derivative with a hexadecyl ether and a hexadecanoyl ester chain. This compound is a critical building block in advanced lipid research and formulation science, valued for its structural similarity to natural membrane components. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors for developing liposomal drug delivery systems, creating biomimetic membranes, and studying lipid-protein interactions.
Application
- Liposomal Drug Delivery: A key phospholipid component for formulating stable, long-circulating liposomes to encapsulate and target therapeutic agents.
- Biomimetic Membrane Models: Used to construct artificial lipid bilayers and vesicles for studying membrane biophysics, permeability, and protein insertion.
- Cell Biology & Biochemistry Research: Serves as a substrate or structural element in research on lipid metabolism, signaling pathways, and membrane dynamics.
- Cosmetic & Dermal Formulations: Incorporated into high-end cosmetic products as an emollient and skin-conditioning agent that mimics natural skin lipids.
- Diagnostic Reagent Development: Utilized in the preparation of lipid-based reagents for diagnostic assays and imaging techniques.
- Biomaterial Surface Modification: Applied to coat medical devices or implants to improve biocompatibility and reduce immune response.
Basic Information
| Item | Detail |
|---|---|
| Product Name | 1-o-Hexadecyl-2-Hexadecanoyl-Rac-Glycero-3-Phosphocholine |
| CAS No. | 84743-00-0 |
| Molecular Formula | C40H82NO7P |
| Molecular Weight | 720.06 g/mol |
| Synonyms | 1-Hexadecyl-2-palmitoyl-rac-glycero-3-phosphocholine; Rac-Pam-PC; C16:0 Alkyl, C16:0 Acyl PC; 1-O-Hexadecyl-2-palmitoyl-sn-glycero-3-phosphocholine (racemic); DPPC analog (ether-linked); 1-O-Cetyl-2-palmitoyl-rac-glycero-3-phosphocholine; Hexadecyl palmitoyl phosphocholine; Synthetic phospholipid 84743-00-0 |
| EINECS | Contact for details |
Quality Control
Our 1-o-Hexadecyl-2-Hexadecanoyl-Rac-Glycero-3-Phosphocholine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and formulation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting critical parameters such as assay, related substances, and residual solvents.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. This material is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to prevent condensation and moisture uptake.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder or waxy solid |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Assay (HPLC) | ≥ 95.0% |
| Related Substances (HPLC) | Total impurities ≤ 5.0% |
| Water Content (KF) | ≤ 2.0% |
| Residual Solvents (GC) | Meets ICH guidelines |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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