Description

4-Nitrophenyl 2-Fucopyranosyl-Fucopyranoside is a specialized synthetic glycoside derivative, primarily utilized as a chromogenic substrate in enzymatic assays. This compound matters for its high specificity and sensitivity in detecting and quantifying the activity of α-L-fucosidase enzymes, a critical biomarker in various biochemical and diagnostic research. It is essential for researchers and manufacturers in the fields of clinical diagnostics, biochemical research, and pharmaceutical development who require reliable and high-purity substrates for enzyme kinetics and inhibitor studies.

Application

• Enzymatic Substrate for α-L-Fucosidase: Primary use as a chromogenic substrate in spectrophotometric assays to measure α-L-fucosidase activity in biological samples.
• Clinical Diagnostics: Used in the development of diagnostic kits for lysosomal storage disorders, such as fucosidosis, and other conditions linked to altered fucosidase levels.
• Biochemical Research: Essential tool for studying enzyme kinetics, inhibition, and the role of fucosidases in glycosylation pathways, cell signaling, and cancer research.
• Pharmaceutical Screening: Employed in high-throughput screening (HTS) platforms to identify and evaluate potential therapeutic inhibitors of α-L-fucosidase.
• Quality Control in Biomanufacturing: Used to monitor and ensure the consistency and activity of enzyme preparations used in bioprocessing.
• Academic Research: A key reagent for universities and research institutes investigating glycobiology, enzymology, and metabolic diseases.

Basic Information

Product Name	4-Nitrophenyl 2-Fucopyranosyl-Fucopyranoside
CAS No.	84730-06-3
Molecular Formula	C18H23NO11
Molecular Weight	429.38 g/mol
Synonyms	p-Nitrophenyl α-L-Fucopyranosyl-(1→2)-α-L-fucopyranoside; 4-Nitrophenyl 2-O-α-L-fucopyranosyl-α-L-fucopyranoside; α-L-Fucopyranosyl-(1→2)-α-L-fucopyranoside 4-nitrophenyl ester; PNPGly-α-(1→2)-Fuc; 4-Nitrophenyl 2-O-(α-L-fucopyranosyl)-α-L-fucopyranoside; Fucosidase Substrate; α-L-Fucosidase Chromogenic Substrate
EINECS	Contact for details

Quality Control

Our 4-Nitrophenyl 2-Fucopyranosyl-Fucopyranoside is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for sensitive research applications. Each lot undergoes rigorous analytical testing, including HPLC for purity, spectral identification (IR, NMR), and specific enzymatic activity validation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and performance.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Specific Rotation	Contact for details
Enzymatic Activity	Suitable for α-L-fucosidase assays
Solubility	Soluble in water, DMSO, DMF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.