Description

2-Phenyl-1-Propyl Glucuronide is a high-purity glucuronide conjugate, a crucial metabolite in drug metabolism and pharmacokinetic (DMPK) studies. Its primary value lies in serving as a definitive analytical reference standard for the quantification and characterization of parent drug compounds and their metabolic pathways. This compound is essential for researchers and quality control laboratories in the pharmaceutical, biotechnology, and contract research organization (CRO) sectors, where precise metabolite identification is critical for drug development and safety assessments.

Application

• Pharmaceutical Reference Standard: Primary use as a certified reference material (CRM) for calibrating analytical instruments in bioanalytical assays.
• Drug Metabolism & Pharmacokinetics (DMPK): Used in in vitro and in vivo studies to investigate the glucuronidation metabolic pathway of drug candidates.
• Toxicology Studies: Employed to identify and quantify specific metabolites for safety and toxicity profiling of new chemical entities.
• Biomarker Research: Acts as a standard in the development of diagnostic methods for detecting drug exposure or metabolic disorders.
• Method Development & Validation: Critical for developing and validating High-Performance Liquid Chromatography (HPLC) and Liquid Chromatography-Mass Spectrometry (LC-MS/MS) methods.
• Quality Control (QC) Testing: Used by pharmaceutical manufacturers to ensure the consistency and purity of active pharmaceutical ingredients (APIs) and their metabolite profiles.

Basic Information

Product Name	2-Phenyl-1-Propyl Glucuronide
CAS No.	84718-96-7
Molecular Formula	C₁₅H₂₀O₇
Molecular Weight	312.32 g/mol
Synonyms	1-Phenyl-2-propyl β-D-glucopyranosiduronic acid; 2-Phenylpropyl glucuronide; β-D-Glucopyranosiduronic acid, 1-phenyl-2-propyl; Phenylpropyl glucuronide; Glucuronide conjugate of 2-phenyl-1-propanol; 84718-96-7; 1-Phenyl-2-propyl-β-D-glucuronide
EINECS	Contact for details

Quality Control

Our 2-Phenyl-1-Propyl Glucuronide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and analytical applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and chromatographic data is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity. For long-term storage, consider desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.