Description

Clebopride Maleate is a high-purity pharmaceutical intermediate and active ingredient, specifically the maleate salt form of clebopride. This compound is a selective dopamine D2 receptor antagonist with prokinetic and antiemetic properties, making it a critical component in the development and manufacture of gastrointestinal therapeutics. It is primarily required by pharmaceutical R&D laboratories, API manufacturers, and contract development and manufacturing organizations (CDMOs) focused on producing advanced gastrointestinal motility agents and anti-nausea medications.

Application

• Active Pharmaceutical Ingredient (API) for the formulation of antiemetic and prokinetic drugs.
• Pharmaceutical Intermediate in the synthesis of advanced dopamine antagonist medications.
• Reference Standard for quality control and analytical method development in pharmaceutical laboratories.
• Research & Development of novel therapeutics targeting dopamine receptors for gastrointestinal disorders.
• Preclinical Studies investigating the pharmacokinetics and pharmacodynamics of clebopride-based treatments.

Basic Information

Product Name	Clebopride Maleate
CAS No.	84370-95-6
Molecular Formula	C20H24ClN3O2 • C4H4O4
Molecular Weight	481.92 g/mol
Synonyms	Clebopride Maleate Salt; 4-Amino-5-chloro-N-[1-(3-cyclohexen-1-ylmethyl)-4-piperidinyl]-2-methoxybenzamide maleate; 4-Amino-5-chloro-2-methoxy-N-[1-[(3-cyclohexen-1-yl)methyl]piperidin-4-yl]benzamide (Z)-but-2-enedioate; Clebopridi maleas; Clebopridum maleicum; CAS 84370-95-6
EINECS	Contact for details

Quality Control

Our Clebopride Maleate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent specifications for pharmaceutical use, including identity, purity, and impurity profile. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with relevant standards. We support development and commercial projects requiring material that aligns with ICH guidelines and current Good Manufacturing Practice (cGMP) principles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and purity. The container should be kept tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.