Description

2-Hydroxy-2-(1-Hydroxyethyl)-3-Methylpentanoic Acid [[5,6,7,7A-Tetrahydro-3H-Pyrrolizin]-1-Ylmethyl] Ester is a complex organic ester with a fused pyrrolizine structure, representing a high-value intermediate in advanced chemical synthesis. This compound is critical for research and development in pharmaceutical chemistry, where its unique molecular architecture serves as a key building block. It is primarily sought by fine chemical manufacturers and R&D laboratories specializing in the development of novel active pharmaceutical ingredients (APIs) and other specialty organic molecules.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of complex drug candidates, particularly those containing pyrrolizidine alkaloid frameworks.
• Fine Chemical Synthesis: Used as a specialized building block for constructing complex esters and lactones in advanced organic chemistry research.
• Biochemical Research: Employed in the study of enzyme inhibitors and receptor ligands due to its specific stereochemistry and functional groups.
• Process Development: Utilized in scaling up synthetic routes from laboratory to pilot plant scale for new chemical entities.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	2-Hydroxy-2-(1-Hydroxyethyl)-3-Methylpentanoic Acid [[5,6,7,7A-Tetrahydro-3H-Pyrrolizin]-1-Ylmethyl] Ester
CAS No.	84306-92-3
Molecular Formula	C16H25NO4
Molecular Weight	295.38 g/mol
Synonyms	1-[[(2-Hydroxy-2-(1-hydroxyethyl)-3-methyl-1-oxopentyl)oxy]methyl]-5,6,7,7a-tetrahydro-3H-pyrrolizine; (5,6,7,7a-Tetrahydro-3H-pyrrolizin-1-yl)methyl 2-hydroxy-2-(1-hydroxyethyl)-3-methylpentanoate; 2-Hydroxy-2-(1-Hydroxyethyl)-3-Methylpentanoic Acid (5,6,7,7a-Tetrahydro-3H-pyrrolizin-1-yl)methyl Ester; Pyrrolizine-1-methanol, α-(1-hydroxyethyl)-α-hydroxy-β-methylpentanoate (ester), hexahydro-; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our production of 2-Hydroxy-2-(1-Hydroxyethyl)-3-Methylpentanoic Acid [[5,6,7,7A-Tetrahydro-3H-Pyrrolizin]-1-Ylmethyl] Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We operate under a cGMP-compliant quality system for pharmaceutical-grade material, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area %)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.