Description

8-((1,1'-Biphenyl)-4-Ylamino)-2'-Deoxyadenosine is a modified nucleoside analog, a key building block in advanced pharmaceutical and biochemical research. This compound is valued for its role as a precursor in the synthesis of oligonucleotides and nucleotide-based therapeutics, where precise molecular structure is critical for biological activity. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies focused on developing novel antiviral agents, anticancer drugs, and molecular probes.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel nucleoside-based antiviral and anticancer drug candidates.
• Biochemical Research: Used as a modified building block for oligonucleotide synthesis in studies of DNA/RNA structure, function, and repair mechanisms.
• Proteomics & Genomics: Serves as a specialized reagent in the development of molecular probes and diagnostic assays.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the pharmacokinetic and pharmacodynamic properties of nucleotide analogs.
• Academic Research: Utilized in university and institutional labs for fundamental research in nucleic acid chemistry and enzymology.

Basic Information

Product Name	8-((1,1'-Biphenyl)-4-Ylamino)-2'-Deoxyadenosine
CAS No.	84283-09-0
Molecular Formula	C24H24N6O3
Molecular Weight	444.49 g/mol
Synonyms	8-([1,1'-Biphenyl]-4-ylamino)-2'-deoxyadenosine; 8-(Biphenyl-4-ylamino)-2'-deoxyadenosine; 2'-Deoxy-N-(4-phenylphenyl)adenosine; 8-(4-Biphenylylamino)-2'-deoxyadenosine; N6-(Biphenyl-4-yl)-2'-deoxyadenosine (common misassignment); 8-(Biphenyl-4-ylamino)deoxyadenosine; dA(Biph) derivative
EINECS	Contact for details

Quality Control

Our 8-((1,1'-Biphenyl)-4-Ylamino)-2'-Deoxyadenosine is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent control of residual solvents and impurities. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.