Description

Guanosine, 8-((1,1'-Biphenyl)-4-Ylamino)-2'-Deoxy- is a chemically modified nucleoside analog, where a biphenylamino group is attached at the 8-position of the guanosine base. This specific structural modification makes it a valuable intermediate and building block in advanced pharmaceutical research and development. It is primarily sought after by research institutions and pharmaceutical companies engaged in the synthesis of novel therapeutic agents, particularly for applications in oncology and antiviral drug discovery.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel nucleoside-based drug candidates.
• Antiviral Research: Used in the development of potential antiviral compounds targeting viral polymerases.
• Oncology Research: Investigated for the creation of chemotherapeutic agents and targeted cancer therapies.
• Biochemical Probe: Serves as a tool compound in molecular biology to study nucleic acid interactions and enzyme mechanisms.
• Chemical Biology: Employed in the synthesis of labeled nucleotides for diagnostic assays and imaging.
• Academic Research: Utilized in universities and research institutes for fundamental studies in medicinal chemistry.

Basic Information

Item	Detail
Product Name	Guanosine, 8-((1,1'-Biphenyl)-4-Ylamino)-2'-Deoxy-
CAS No.	84283-08-9
Molecular Formula	C23H22N6O4
Molecular Weight	446.46 g/mol
Synonyms	8-[(1,1'-Biphenyl)-4-ylamino]-2'-deoxyguanosine; 2'-Deoxy-8-[(1,1'-biphenyl)-4-ylamino]guanosine; 8-(Biphenyl-4-ylamino)-2'-deoxyguanosine; 8-(4-Biphenylylamino)-2'-deoxyguanosine; dG-Biphenylamine derivative; Modified 2'-Deoxyguanosine; Biphenylamino-deoxyguanosine; Research Grade Nucleoside Analog
EINECS	Contact for details

Quality Control

Our Guanosine, 8-((1,1'-Biphenyl)-4-Ylamino)-2'-Deoxy- is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS). We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes to ensure compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.