Description

1-Palmitoyl-2-(10,12-Tricosadiynoyl)-Sn-Glycero-3-Phosphocholine is a synthetic, diacetylenic phospholipid, a key building block in advanced biomembrane research and materials science. Its unique structure, featuring a polymerizable diacetylene group in the *sn-2* acyl chain, makes it an essential material for creating stable, functionalized lipid bilayers and vesicles. This high-purity lipid is primarily utilized by researchers and product developers in the pharmaceutical, biotechnology, and nanotechnology sectors for applications ranging from drug delivery system modeling to the fabrication of biosensors and biomimetic membranes.

Application

• Liposome & Biomembrane Research: A critical component for constructing polymerizable liposomes and planar bilayer membranes to study membrane dynamics, stability, and permeability.
• Drug Delivery System Development: Used to create stable, controlled-release vesicle carriers for encapsulating active pharmaceutical ingredients (APIs) in preclinical studies.
• Biosensor Fabrication: Serves as a foundational material for immobilizing enzymes or receptors on sensor surfaces, leveraging its ability to form stable, ordered films.
• Biomimetic Material Science: Employed in the synthesis of advanced materials that mimic natural cell membranes for tissue engineering and diagnostic devices.
• Photopolymerization Studies: The diacetylene moiety allows for UV-induced polymerization, making it valuable for research into photoresponsive materials and switchable membrane properties.
• Model Membrane Systems: Provides a well-defined, synthetic lipid for investigating lipid-protein interactions, raft formation, and other fundamental biophysical processes.

Basic Information

Product Name	1-Palmitoyl-2-(10,12-Tricosadiynoyl)-Sn-Glycero-3-Phosphocholine
CAS No.	84271-00-1
Molecular Formula	C46H85NO8P
Molecular Weight	811.14 g/mol
Synonyms	Polymerizable Phosphatidylcholine; Diacetylenic Phosphatidylcholine; 1-Palmitoyl-2-tricosadiynoyl-sn-glycero-3-phosphocholine; PC(16:0/23:2(10,12-diyne)); DCPC (Diacetylenic Phosphatidylcholine); 1-Hexadecanoyl-2-(10,12-tricosadiynoyl)-sn-glycero-3-phosphocholine; (2R)-2-[(10,12-Tricosadiynoyl)oxy]-3-(palmitoyloxy)propyl 2-(trimethylammonio)ethyl phosphate
EINECS	Contact for details

Quality Control

Our 1-Palmitoyl-2-(10,12-Tricosadiynoyl)-Sn-Glycero-3-Phosphocholine is produced under strict quality management protocols to ensure batch-to-batch consistency and high chemical purity suitable for sensitive research applications. Each lot undergoes comprehensive analytical characterization, including chromatographic purity assays and structural confirmation. Certificates of Analysis (COA) detailing specific results for identity, purity, and related substances are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store unopened vials at -20°C or below under an inert atmosphere (e.g., argon or nitrogen). This product is hygroscopic (moisture-sensitive) and easily oxidized; allow the sealed container to equilibrate to room temperature before opening to minimize moisture condensation. Once opened, purge the container with inert gas and reseal immediately.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Solubility	Soluble in chloroform, ethanol; forms liposomes in aqueous buffers
Loss on Drying	≤ 2.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.