Description

n-Succinyldesferrioxamine B is a chemically modified derivative of the potent iron-chelating agent desferrioxamine B. This compound is engineered to enhance stability and alter pharmacokinetic properties, making it a valuable tool in biochemical and pharmaceutical research. It is primarily utilized by researchers and manufacturers in the fields of metal chelation therapy, molecular biology, and diagnostic agent development.

Application

• Biochemical Research: Used as a specific iron chelator in studies of iron metabolism, oxidative stress, and metal-dependent enzyme function.
• Pharmaceutical Intermediates: Serves as a key precursor or active component in the development of novel therapeutic chelating agents.
• Diagnostic Agent Formulation: Employed in the preparation of contrast agents or probes for medical imaging and in vitro diagnostics.
• Microbiology: Applied in microbial growth media to create iron-limited conditions for studying bacterial siderophore systems.
• Cell Culture: Utilized to manipulate intracellular iron levels in mammalian cell culture experiments.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	n-Succinyldesferrioxamine B
CAS No.	84211-47-2
Molecular Formula	C27H48N6O10
Molecular Weight	616.71 g/mol
Synonyms	Succinyl Desferrioxamine B; N-Succinyl Desferrioxamine B; N-Succinyldesferrioxamine B; SDFO; N-SDFO; N-Succinyl-DFO; N-Hydroxysuccinimide ester derivative of Desferrioxamine B (precursor); N5-(3-Carboxy-1-oxopropyl)-N10-hydroxy-N1,N14-di(5-aminopentyl)-3,6,9,12-tetraoxapentadecanediamide
EINECS	Contact for details

Quality Control

Our n-Succinyldesferrioxamine B is produced under a rigorous quality management system. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and heavy metals. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. Due to its hygroscopic nature, the container should be kept in a desiccated environment. Allow the product to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.