Description

Ethenoadenosine Triphosphate-2',3'-Dialdehyde is a chemically modified nucleotide analog, specifically a reactive dialdehyde derivative of ATP. This compound is a critical cross-linking reagent and affinity label used in biochemical research to study enzyme active sites and nucleotide-binding proteins. It is primarily utilized by research scientists and process developers in the pharmaceutical, biotechnology, and life science research sectors for probing protein structure and function.

Application

• Biochemical Cross-linking Agent: Used to covalently modify and map nucleotide-binding domains in enzymes and receptors.
• Affinity Labeling Studies: Essential for investigating the structure and mechanism of ATP-utilizing proteins like kinases and ATPases.
• Enzyme Inhibition Research: Serves as a mechanism-based inhibitor to study catalytic pathways.
• Proteomics and Structural Biology: A tool for protein footprinting and analyzing protein-ligand interactions.
• Diagnostic Reagent Development: Used in the development of assays and biosensors targeting ATP-binding events.
• Pharmaceutical R&D: Employed in early-stage drug discovery for target validation and hit identification.

Basic Information

Product Name	Ethenoadenosine Triphosphate-2',3'-Dialdehyde
CAS No.	84184-92-9
Molecular Formula	C₁₂H₁₅N₅O₁₂P₃
Molecular Weight	562.18 g/mol
Synonyms	2',3'-Dialdehyde ATP; Etheno-ATP dialdehyde; 1,N6-Ethenoadenosine-5'-triphosphate-2',3'-dialdehyde; Reactive ATP analog; Periodate-oxidized etheno-ATP; ε-ATP-2',3'-dialdehyde; ATP affinity label
EINECS	Contact for details

Quality Control

Our Ethenoadenosine Triphosphate-2',3'-Dialdehyde is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and stability parameters. We adhere to rigorous internal quality standards to meet the exacting requirements of the research community.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term stability, store under inert atmosphere. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 3.0%
Solubility	Soluble in aqueous buffer, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.