Description

9,10-Dihydro-9-Glutathionyl-10-Hydroxyphenanthrene is a specialized biochemical conjugate formed from phenanthrene and the tripeptide glutathione. This compound is of significant interest in biochemical and toxicological research as a specific biomarker for exposure to polycyclic aromatic hydrocarbons (PAHs). It is primarily utilized by research institutions, diagnostic laboratories, and pharmaceutical companies engaged in studies of metabolic pathways, oxidative stress, and environmental toxicology.

Application

• Biomarker Research: Used as a reference standard for the detection and quantification of PAH-DNA adducts and related metabolites in biological samples.
• Toxicology Studies: Essential for investigating the metabolic activation and detoxification pathways of phenanthrene and related compounds.
• Environmental Monitoring: Serves as a critical analytical standard in assays designed to assess human and ecological exposure to airborne and waterborne pollutants.
• Oxidative Stress Analysis: Employed in studies examining glutathione-mediated cellular defense mechanisms against electrophilic toxicants.
• Method Development & Validation: Used to calibrate analytical instruments (e.g., LC-MS/MS, HPLC) for high-sensitivity bioanalytical methods.
• Pharmaceutical R&D: Supports research into chemopreventive agents and therapies targeting metabolism-related diseases.

Basic Information

Product Name	9,10-Dihydro-9-Glutathionyl-10-Hydroxyphenanthrene
CAS No.	84107-69-7
Molecular Formula	C28H33N3O9S
Molecular Weight	587.64 g/mol
Synonyms	9,10-Dihydro-9-S-glutathionyl-10-hydroxyphenanthrene; 9,10-Dihydroxy-9,10-dihydrophenanthrene-9-glutathione conjugate; Phenanthrene-9,10-dihydrodiol-9-glutathione; GSH-Phenanthrene Dihydrodiol Adduct; 9-Glutathionyl-10-hydroxy-9,10-dihydrophenanthrene; Phenanthrene glutathione conjugate; CAS 84107-69-7
EINECS	Contact for details

Quality Control

Our 9,10-Dihydro-9-Glutathionyl-10-Hydroxyphenanthrene is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the exacting standards required for research applications. A Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. This compound is easily oxidized and light-sensitive; allow it to reach room temperature in a desiccator before opening to minimize moisture uptake and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, Methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.