Description

25-Hydroxyvitamin D3-26,23-Peroxylactone is a specialized oxidized metabolite of vitamin D3, characterized by its unique peroxylactone structure. This compound is of significant interest in biochemical research and pharmaceutical development for studying vitamin D metabolism and oxidative pathways. It serves as a critical reference standard and intermediate for researchers and manufacturers in the pharmaceutical, nutraceutical, and life science sectors requiring high-purity analytical materials.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the calibration of analytical instruments and validation of assay methods in drug development and quality control laboratories.
• Biochemical Research: A vital tool for investigating the oxidative metabolism and catabolic pathways of vitamin D3 and its analogs in metabolic studies.
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a key synthetic precursor in the production of novel vitamin D analogs and related therapeutic compounds.
• Analytical Chemistry: Employed in method development and as an internal standard for High-Performance Liquid Chromatography (HPLC) and Liquid Chromatography-Mass Spectrometry (LC-MS) analysis of vitamin D metabolites.
• Nutraceutical Research: Used in studies aiming to understand the stability, degradation products, and complex biological activity profiles of vitamin D formulations.

Basic Information

Product Name	25-Hydroxyvitamin D3-26,23-Peroxylactone
CAS No.	84070-69-9
Molecular Formula	C₂₇H₄₀O₅
Molecular Weight	444.60 g/mol
Synonyms	(5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-1α,3β,25-triol 26,23-peroxylactone; 25-Hydroxyvitamin D3 26,23-Lactone 23-Peroxide; 25-Hydroxy-26,23-peroxylactone vitamin D3; 25(OH)D3-26,23-Peroxylactone; 1α,25-Dihydroxy-26,23-peroxylactone vitamin D3 (related metabolite); Vitamin D3 peroxylactone metabolite; 23-Peroxy-1α,25-dihydroxyvitamin D3 lactone (alternative naming).
EINECS	Contact for details

Quality Control

Every batch of 25-Hydroxyvitamin D3-26,23-Peroxylactone is manufactured and analyzed under strict quality management systems. Our products undergo rigorous identity, purity, and impurity profile testing using advanced techniques like HPLC, LC-MS, and NMR to ensure compliance with research and pharmaceutical-grade standards. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and degradation. Allow the container to reach room temperature in a desiccator before opening to prevent condensation and moisture uptake. Keep away from strong oxidizers and acids.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Specific Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.