Description

(+/-)5-Hepe CAS NO 83952-40-3 is a high-purity synthetic eicosanoid derivative, specifically a hydroxy-eicosapentaenoic acid (HEPE) analog, valued for its role as a key biochemical intermediate and research tool. Its significance lies in its utility for studying lipid signaling pathways, inflammation, and metabolic processes in advanced life science research. This compound is essential for pharmaceutical R&D laboratories, academic institutions, and fine chemical manufacturers focused on developing novel therapeutics and diagnostic agents.

Application

• Biochemical Research: Serves as a critical reference standard and precursor in the study of eicosanoid biosynthesis, metabolism, and signaling cascades.
• Pharmaceutical Development: Used as an intermediate in the synthesis of potential therapeutic agents targeting inflammatory and metabolic disorders.
• Cell Biology Studies: Employed to investigate the effects of specialized pro-resolving mediators (SPMs) and lipid-derived signaling molecules on cellular function.
• Analytical Chemistry: Functions as a high-purity calibrant and internal standard for quantitative analytical methods such as LC-MS and HPLC in lipidomics.
• Nutritional Science Research: Utilized in studies exploring the biological activity and health impacts of ω-3 fatty acid derivatives.

Basic Information

Product Name	(+/-)5-Hepe
CAS No.	83952-40-3
Molecular Formula	C20H30O3
Molecular Weight	318.45 g/mol
Synonyms	5-HEPE; 5-Hydroxyeicosapentaenoic Acid; (±)-5-Hydroxy-6E,8Z,11Z,14Z,17Z-eicosapentaenoic Acid; all-cis-5-Hydroxy-6,8,11,14,17-eicosapentaenoic Acid; 5-Hydroxyicosa-6,8,11,14,17-pentaenoic Acid; 5-Hydroxy-EPA; 5-HEPE Racemate
EINECS	Contact for details

Quality Control

Our (+/-)5-Hepe is manufactured under strict quality management systems to ensure batch-to-batch consistency and reliability for critical research applications. Each lot undergoes comprehensive analytical characterization, including identity confirmation by spectroscopic methods and purity assessment by chromatographic techniques. A Certificate of Analysis (COA) detailing specific results for purity, identity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Related Substances	≤ 5.0%
Solvent Residue (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.