Description

4-Hydroperoxy-2-Nonenal is a reactive, electrophilic lipid peroxidation product derived from polyunsaturated fatty acids. This compound matters as a critical biochemical intermediate and marker for oxidative stress in biological systems, playing a significant role in cell signaling and damage pathways. Researchers and quality control laboratories in the pharmaceutical, biotechnology, and nutraceutical industries need it for studying oxidative damage mechanisms, developing analytical standards, and investigating the role of lipid-derived aldehydes in disease pathology.

Application

• Biomedical Research: Used as a key standard and reagent in studies of lipid peroxidation, oxidative stress, and redox biology.
• Analytical Chemistry: Serves as a high-purity reference standard for the calibration of HPLC, GC-MS, and LC-MS/MS methods in clinical and research laboratories.
• Pharmaceutical Development: Employed in the investigation of cellular damage pathways and the evaluation of antioxidant drug candidates.
• Nutraceutical & Cosmeceutical Testing: Applied in efficacy studies to test the protective effects of ingredients against lipid peroxidation.
• Toxicology Studies: Utilized to model and understand the mechanisms of toxicity induced by reactive carbonyl species.
• Food Science Research: Acts as a marker for studying oxidative rancidity and quality degradation in lipid-containing food products.

Basic Information

Product Name	4-Hydroperoxy-2-Nonenal
CAS No.	83920-83-6
Molecular Formula	C₉H₁₆O₃
Molecular Weight	172.22 g/mol
Synonyms	4-HPNE; 4-Hydroperoxy-2E-nonenal; (2E)-4-Hydroperoxy-2-nonenal; 4-Hydroperoxy-trans-2-nonenal; Lipid peroxidation product; Oxidized lipid aldehyde; HNE precursor; 4-Hydroperoxynonenal
EINECS	Contact for details

Quality Control

Our 4-Hydroperoxy-2-Nonenal is produced and handled under strict quality protocols to ensure batch-to-batch consistency and reliability for sensitive research applications. Each lot undergoes comprehensive analytical characterization, including purity assay and identity confirmation. A Certificate of Analysis (COA) detailing specific test results is provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) due to its sensitivity to oxidation and thermal degradation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. For long-term stability, store desiccated.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or oil
Identification (IR / NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Solvent Content (Residual)	Meet ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.