Description

Cytidine 5'-(Tetrahydrogen Triphosphate), 3'-Deoxy-, Tetrasodium Salt is a chemically modified nucleotide analog, specifically a 3'-deoxy derivative of cytidine triphosphate (CTP). This compound is a critical biochemical reagent used to inhibit RNA chain elongation, making it an essential tool for molecular biology research and diagnostic applications. It is primarily utilized by researchers and manufacturers in the life sciences, pharmaceutical development, and in vitro diagnostics sectors.

Application

• Molecular Biology Research: Acts as a chain terminator in RNA synthesis studies, particularly useful for sequencing and analyzing RNA polymerase activity.
• Enzymology Studies: Serves as a substrate analog to investigate the mechanisms and kinetics of RNA polymerases and other nucleotide-processing enzymes.
• Diagnostic Assay Development: Used in the formulation of kits for non-radioactive RNA labeling and detection methods.
• Antiviral Research: Investigated for its potential as a nucleoside analog precursor in the study of antiviral compounds targeting viral RNA replication.
• Biochemical Reagent: A key component in controlled in vitro transcription systems to produce specific RNA fragments.

Basic Information

Product Name	Cytidine 5'-(Tetrahydrogen Triphosphate), 3'-Deoxy-, Tetrasodium Salt
CAS No.	83711-63-1
Molecular Formula	C9H12N3Na4O13P3
Molecular Weight	587.08 g/mol (anhydrous basis)
Synonyms	3'-Deoxycytidine-5'-triphosphate tetrasodium salt; 3'-dCTP, Na4; Cordycepin 5'-triphosphate tetrasodium salt (Note: Cordycepin is 3'-deoxyadenosine, this is the cytidine analog); 3'-Deoxy-CTP; Cytidine 5'-(tetrahydrogen triphosphate), 3'-deoxy-, sodium salt (1:4); 3'-Deoxycytidine 5'-triphosphate tetrasodium; 2(1H)-Pyrimidinone, 4-amino-1-[5-O-[hydroxy([hydroxy(phosphonooxy)phosphinyl]oxy)phosphinyl]-3-deoxy-β-D-erythro-pentofuranosyl]-, sodium salt (1:4)
EINECS	Contact for details

Quality Control

Our Cytidine 5'-(Tetrahydrogen Triphosphate), 3'-Deoxy-, Tetrasodium Salt is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for sensitive biochemical applications. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0 %
pH (1% Solution)	6.0 - 8.0
Endotoxin (LAL)	< 10 EU/mg (for molecular biology grade)
Biological Activity	Suitable for use as a chain terminator in in vitro transcription

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.