Description

Thiamine Indole-3-Propionate is a specialized chemical compound formed by the esterification of vitamin B1 (thiamine) with indole-3-propionic acid. This unique molecular structure combines the essential metabolic activity of thiamine with the bioactive properties of the indole moiety, making it a compound of significant interest for advanced research and development. It is primarily sought after by professionals in the pharmaceutical, nutraceutical, and life science sectors for its potential in creating novel therapeutic and nutritional agents.

Application

• Pharmaceutical Intermediates: Serves as a key building block in the synthesis of novel drug candidates, particularly those targeting neurological and metabolic pathways.
• Nutraceutical & Dietary Supplement Research: Investigated for the development of advanced vitamin B1 derivatives with enhanced bioavailability or targeted physiological effects.
• Biochemical Research: Used as a reference standard or reagent in studies exploring thiamine metabolism, enzyme cofactors, and cellular energy processes.
• Cosmeceutical Applications: Explored in R&D for formulating skincare products aimed at improving cellular energy metabolism and antioxidant defense in the skin.
• Agrochemical Research: Potential use in developing plant growth regulators or stress-resistance agents due to the bioactive indole component.

Basic Information

Product Name	Thiamine Indole-3-Propionate
CAS No.	83661-65-8
Molecular Formula	C₁₉H₂₃N₅O₃S
Molecular Weight	401.48 g/mol
Synonyms	Thiamine 3-Indolepropionate; Vitamin B1 Indole-3-Propionate Ester; Thiamine Indolepropanoate; 3-Indolepropionic Acid Thiamine Ester; Thiamine IPA; TIP; ThPPA (Thiamine Propionate Analog); 2-[3-[(4-Amino-2-methylpyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethyl 3-(1H-indol-3-yl)propanoate
EINECS	Contact for details

Quality Control

Our Thiamine Indole-3-Propionate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters including assay, related substances, and residual solvents. While produced to high-purity standards suitable for research, specifications can be aligned with specific project requirements, including potential compliance with in-house pharmacopeial guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and opened under conditions of low humidity to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.