Description

Fluorescein Mono-p-Guanidinobenzoate Hydrochloride is a chemically modified derivative of fluorescein, designed for high-affinity biological targeting. This compound is crucial for researchers and developers requiring precise, fluorescent labeling in diagnostic and biochemical assays. It is primarily utilized in the life sciences, pharmaceutical research, and diagnostic reagent manufacturing sectors.

Application

• Protease Activity Assays: Acts as a sensitive fluorogenic substrate for the detection and quantification of trypsin-like serine proteases.
• Diagnostic Reagent Development: Used in the formulation of fluorescent probes and kits for clinical diagnostics and point-of-care testing.
• Biochemical Research: Serves as a key reagent in enzyme kinetics studies and inhibitor screening for drug discovery.
• Cell Biology Studies: Employed in fluorescent imaging techniques to visualize and study protease activity in live cells.
• Quality Control in Biologics: Used in purity and activity testing of therapeutic enzymes and other protein-based pharmaceuticals.

Basic Information

Item	Detail
Product Name	Fluorescein Mono-p-Guanidinobenzoate Hydrochloride
CAS No.	83616-10-8
Molecular Formula	C29H21ClN4O7
Molecular Weight	572.95 g/mol
Synonyms	Fluorescein Mono-p-Guanidinobenzoate HCl; FMGB-HCl; p-Guanidinobenzoic Acid Fluorescein Ester Hydrochloride; Fluorescein Guanidinobenzoate Hydrochloride; Boc-Gly-Pro-Arg-MCA (related protease substrate class); Fluorogenic Protease Substrate; 4-Guanidinobenzoic Acid Fluorescein Derivative Hydrochloride
EINECS	Contact for details

Quality Control

Our Fluorescein Mono-p-Guanidinobenzoate Hydrochloride is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and diagnostic applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. The product is hygroscopic (moisture-sensitive) and light-sensitive; ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	Orange to red powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines
Biological Activity (Fluorogenic Assay)	Conforms to reference

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.