Description

6'-o-4-Azidobenzoylatractyloside is a chemically modified derivative of the natural compound atractyloside, featuring a photoactivatable azidobenzoyl group. This modification is critical for its primary use as a biochemical probe in mitochondrial research, specifically for studying the adenine nucleotide translocator (ANT). Researchers in pharmaceutical development and biochemistry utilize this compound for photoaffinity labeling experiments to investigate protein-ligand interactions and mitochondrial function.

Application

• Photoaffinity Labeling Probe: Used to covalently label and study the adenine nucleotide translocator (ANT) in mitochondrial membranes.
• Mitochondrial Research: A key tool for investigating mitochondrial permeability transition pore (MPTP) formation and regulation.
• Biochemical Mechanism Studies: Employed to elucidate the binding sites and mechanisms of action for cardioprotective and cytotoxic agents.
• Pharmaceutical Development: Supports target identification and validation in drug discovery programs focused on metabolic diseases and ischemia-reperfusion injury.
• Academic Research: Essential for basic science studies in cell biology, apoptosis, and energy metabolism.

Basic Information

Product Name	6'-o-4-Azidobenzoylatractyloside
CAS No.	83579-68-4
Molecular Formula	C34H43N5O13S
Molecular Weight	761.80 g/mol
Synonyms	4-Azidobenzoyl Atractyloside; 6'-O-(4-Azidobenzoyl)atractyloside; Atractyloside 6'-(4-azidobenzoate); Atractyloside, 6'-(4-azidobenzoate); Azidobenzoylatractyloside; Photoaffinity Atractyloside; ANT Photoaffinity Label; Mitochondrial Probe 83579-68-4
EINECS	Contact for details

Quality Control

Our 6'-o-4-Azidobenzoylatractyloside is produced under strict quality management protocols to ensure batch-to-batch consistency and high chemical purity suitable for sensitive research applications. Identity and purity are confirmed by advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This compound is hygroscopic (moisture-sensitive) and light-sensitive. Allow the container to reach room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.