Description

1-(Benzyloxycarbonyl)-L-Prolyl-N5-Carbamoyl-n-(4-Nitrophenyl)-L-Ornithinamide is a specialized, high-purity synthetic peptide derivative designed for advanced research and development. This compound matters as a critical building block and intermediate in the synthesis of complex peptide-based pharmaceuticals and biochemical probes. It is primarily needed by pharmaceutical R&D laboratories, biotechnology companies, and academic research institutions focused on protease inhibitor development, peptide chemistry, and novel therapeutic agent discovery.

Application

• Pharmaceutical Intermediate: Key synthetic precursor in the development of novel peptide-based drugs and protease inhibitors.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly for investigating protease activity and specificity.
• Peptide Synthesis: Serves as a protected amino acid derivative in solid-phase and solution-phase peptide synthesis (SPPS).
• Medicinal Chemistry: A valuable scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Diagnostic Development: Potential use in developing assay components for clinical diagnostics targeting specific enzymatic pathways.
• Academic Research: Employed in university and institutional labs for fundamental studies in biochemistry, enzymology, and chemical biology.

Basic Information

Item	Detail
Product Name	1-(Benzyloxycarbonyl)-L-Prolyl-N5-Carbamoyl-n-(4-Nitrophenyl)-L-Ornithinamide
CAS No.	83575-44-4
Molecular Formula	C25H30N6O7
Molecular Weight	526.54 g/mol
Synonyms	Z-Pro-Orn(N5-Cbz)-pNA; Cbz-Pro-Orn(N5-Cbz)-p-Nitroanilide; 1-(Benzyloxycarbonyl)-L-prolyl-N5-carbamoyl-N-(4-nitrophenyl)-L-ornithinamide; Z-Pro-Orn(Cbz)-pNA; Chromogenic Substrate for Proteases; Peptide p-Nitroanilide (pNA) Substrate; L-Ornithinamide, N-(4-nitrophenyl)-, N5-[[(phenylmethoxy)carbonyl]amino]-; 1-[(Phenylmethoxy)carbonyl]-L-prolyl-N5-[[(phenylmethoxy)carbonyl]amino]-N-(4-nitrophenyl)-
EINECS	Contact for details

Quality Control

Our 1-(Benzyloxycarbonyl)-L-Prolyl-N5-Carbamoyl-n-(4-Nitrophenyl)-L-Ornithinamide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the stringent requirements of pharmaceutical and biotechnology partners.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label. This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0% (Total peak area)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.