Description

Deoxypyridinoline CAS NO 83462-55-9 is a specific pyridinium crosslink compound that serves as a critical biochemical marker for bone resorption and collagen degradation. Its precise quantification is essential for research into metabolic bone diseases, osteoporosis, and connective tissue disorders. This high-purity reference standard is primarily required by pharmaceutical R&D laboratories, clinical diagnostics manufacturers, and academic institutions conducting advanced biochemical studies.

Application

• Biochemical Research Standard: Used as a certified reference material (CRM) for calibrating analytical instruments in bone metabolism studies.
• Clinical Diagnostics Development: A key calibrant and control in the development of immunoassays and HPLC-MS/MS kits for measuring bone turnover markers in human serum or urine.
• Pharmaceutical R&D: Employed in preclinical and clinical trials to evaluate the efficacy of new osteoporosis drugs, anti-resorptive agents, and treatments for Paget's disease.
• Metabolic Disorder Studies: Critical for investigating the pathophysiology of conditions like osteogenesis imperfecta, rheumatoid arthritis, and bone metastases.
• Quality Control in Manufacturing: Serves as a system suitability standard in the quality control of diagnostic reagent production.
• Academic Research: Used in university and institutional labs for fundamental research on collagen catabolism and connective tissue biology.

Basic Information

Item	Detail
Product Name	Deoxypyridinoline
CAS No.	83462-55-9
Molecular Formula	C18H28N4O8
Molecular Weight	428.44 g/mol
Synonyms	Deoxypyridinoline; DPD; Deoxy-PYD; Lysylpyridinoline; 2,4-Diamino-3-hydroxy-1,5-bis(3-aminopropyl)pentane-1,5-dione; Bone collagen crosslink; Pyridinoline, deoxy-; Free Deoxypyridinoline
EINECS	Contact for details

Quality Control

Our Deoxypyridinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, mass spectrometry for structural confirmation, and residual solvent analysis to ensure it meets the stringent requirements for research and diagnostic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and assay is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant or under an inert atmosphere. Keep the container sealed when not in use to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC-MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.