Description

3'-Deoxysangivamycin is a structurally defined nucleoside analog with significant biochemical research applications. This compound is valued for its role as a potent and selective inhibitor of protein kinases, particularly CK2, making it a crucial tool for studying cellular signaling pathways. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies engaged in oncology research, enzymology studies, and the development of novel therapeutic agents.

Application

• Biochemical Research: As a selective protein kinase CK2 inhibitor for studying phosphorylation mechanisms and signal transduction.
• Oncology & Cancer Research: Investigation of anti-proliferative effects and potential as a lead compound for novel chemotherapeutic agents.
• Enzymology Studies: Tool compound for in vitro assays to determine kinase activity and screen for enzyme inhibitors.
• Pharmaceutical Development: Intermediate or reference standard in the discovery and development of targeted cancer therapies.
• Academic Research: Used in university and institutional labs for fundamental studies on cell cycle regulation and apoptosis.
• Biomarker Discovery: Aid in exploring the role of specific kinases in disease pathology for diagnostic applications.

Basic Information

Product Name	3'-Deoxysangivamycin
CAS No.	83379-31-1
Molecular Formula	C15H15N5O4
Molecular Weight	329.31 g/mol
Synonyms	3'-Deoxysangivamycin; Sangivamycin, 3'-deoxy-; 7-Deaza-3'-deoxyadenosine derivative; 4-Amino-5-carboxamido-7-(3-deoxy-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine; Protein Kinase CK2 Inhibitor; NSC 65346; CK2 Inhibitor III
EINECS	Contact for details

Quality Control

Our 3'-Deoxysangivamycin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with research-grade specifications. We support cGMP standards for active pharmaceutical ingredient (API) development.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, cool place. This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a desiccated environment to maintain stability and purity. Avoid prolonged exposure to high humidity.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.