Description

n-(3-(3-Iodo-4-Hydroxybenzyl)Propionyl)-1,2-Dipalmitoylphosphatidylethanolamine is a specialized, high-purity phospholipid derivative designed for advanced research and development applications. This compound matters as a critical building block for creating targeted drug delivery systems and diagnostic agents, leveraging its unique iodinated phenolic headgroup for conjugation and labeling. It is primarily needed by pharmaceutical researchers, biotech companies, and diagnostic developers working on liposomal formulations, targeted therapies, and molecular imaging probes.

Application

• Liposome and Nanoparticle Functionalization: Acts as a key anchor molecule for attaching targeting ligands (e.g., antibodies, peptides) or imaging agents to lipid-based drug delivery carriers.
• Targeted Drug Delivery Systems: Used in the synthesis of ligand-conjugated phospholipids for active targeting of therapeutics to specific cells or tissues, such as tumors.
• Molecular Imaging Probe Development: The iodine atom provides a handle for radiolabeling (e.g., with I-125) for use in SPECT imaging or as a heavy atom contrast agent in other modalities.
• Bioconjugation and Surface Modification: Serves as a reactive intermediate for coupling biomolecules to lipid membranes or surfaces in biosensor and microarray development.
• Model Membrane Studies: Employed in biophysical research to study the incorporation and effects of modified lipids on membrane structure and function.
• Precursor for Further Chemical Synthesis: Used as a starting material for the preparation of other complex, functionalized phospholipid derivatives.

Basic Information

Product Name	n-(3-(3-Iodo-4-Hydroxybenzyl)Propionyl)-1,2-Dipalmitoylphosphatidylethanolamine
CAS No.	83016-61-9
Molecular Formula	C49H87INO10P
Molecular Weight	984.08 g/mol
Synonyms	1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[3-(3-iodo-4-hydroxybenzyl)propionyl]; DPPE-IHP; Iodinated DPPE Derivative; N-[3-(3-Iodo-4-hydroxybenzyl)propionyl]-1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine; Phospholipid-PE-Iodo Phenol Conjugate; Functionalized DPPE; 3-Iodo-4-hydroxybenzylpropionyl-DPPE; PE-Derivatized Lipid with Iodophenol Group
EINECS	Contact for details

Quality Control

Our n-(3-(3-Iodo-4-Hydroxybenzyl)Propionyl)-1,2-Dipalmitoylphosphatidylethanolamine is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity, essential for sensitive research applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the stringent requirements of pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to maintain stability. This product is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after each use to minimize exposure to atmospheric moisture. For long-term storage, desiccants are recommended.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥95.0%
Related Substances (HPLC)	Total impurities ≤5.0%
Solvent Residue (GC)	Meets ICH guidelines
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.