Description

(S)-(+)-(2,2-Dimethyl-[1,3]-Dioxolan-4-Yl)-Methylamine is a high-value chiral building block and intermediate, specifically the (S)-enantiomer of a protected amino alcohol derivative. Its primary commercial value lies in its role as a key precursor for the synthesis of complex pharmaceutical agents, particularly those requiring stereochemical control. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and fine chemical industries who require high-purity, enantiomerically pure intermediates for asymmetric synthesis.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), including antiviral drugs, β-blockers, and other therapeutics.
• Asymmetric Synthesis: Used as a chiral auxiliary or ligand precursor in catalytic asymmetric reactions to induce enantioselectivity.
• Agrochemical Synthesis: Serves as a building block for creating enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances where specific stereochemistry is required.
• Academic & Industrial R&D: A valuable reagent for method development and exploring new synthetic pathways in organic and medicinal chemistry.

Basic Information

Product Name	(S)-(+)-(2,2-Dimethyl-[1,3]-Dioxolan-4-Yl)-Methylamine
CAS No.	82954-65-2
Molecular Formula	C6H13NO2
Molecular Weight	131.17 g/mol
Synonyms	(S)-(+)-2-Amino-1,3-propanediol acetonide; (S)-2,2-Dimethyl-1,3-dioxolane-4-methanamine; (S)-4-(Aminomethyl)-2,2-dimethyl-1,3-dioxolane; (S)-1-Amino-2,3-O-isopropylidene glycerol; (S)-Isopropylidene glyceramine; (S)-Solketal amine; (S)-Glycerol acetonide amine; (S)-2,2-Dimethyl-4-aminomethyl-1,3-dioxolane
EINECS	Contact for details

Quality Control

Our (S)-(+)-(2,2-Dimethyl-[1,3]-Dioxolan-4-Yl)-Methylamine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting standards for pharmaceutical and fine chemical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for prolonged operations to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.