Description

Guanosine, 8-(Acetyl(4'-(Acetylamino)(1,1'-Biphenyl)-4-Yl)Amino)-2'-Deoxy- is a chemically modified nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block and a key intermediate in the synthesis of novel therapeutic agents, particularly those targeting specific enzymatic pathways. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of antiviral drugs, anticancer therapies, and other nucleotide-based pharmaceuticals. The precise modification of the guanosine structure allows for targeted interaction with biological systems, making it a valuable tool for medicinal chemists.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel nucleotide analog drugs for antiviral and anticancer applications.
• Medicinal Chemistry Research: Used as a specialized building block for structure-activity relationship (SAR) studies and lead optimization.
• Biochemical Probe Development: Employed in the creation of probes to study enzyme mechanisms, particularly those involving polymerases and kinases.
• Antiviral Drug Discovery: Investigated as a core component in the development of therapeutics targeting viral replication.
• Oncology Research: Explored for its potential in designing compounds that interfere with DNA synthesis in rapidly dividing cells.
• Academic & Contract Research: Supplied to universities and CROs for fundamental research in nucleotide chemistry and drug design.

Basic Information

Item	Details
Product Name	Guanosine, 8-(Acetyl(4'-(Acetylamino)(1,1'-Biphenyl)-4-Yl)Amino)-2'-Deoxy-
CAS No.	82682-90-4
Molecular Formula	C31H31N7O6
Molecular Weight	597.62 g/mol
Synonyms	8-[N-Acetyl-N-[4'-(acetylamino)[1,1'-biphenyl]-4-yl]amino]-2'-deoxyguanosine; 2'-Deoxy-8-[N-acetyl-N-[4'-(acetylamino)-4-biphenylyl]amino]guanosine; 8-(Acetyl(4'-(Acetylamino)[1,1'-Biphenyl]-4-Yl)Amino)-2'-Deoxyguanosine; Modified 2'-Deoxyguanosine Derivative; Biphenyl-modified dG Analog; Research Grade Nucleoside Intermediate; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our Guanosine, 8-(Acetyl(4'-(Acetylamino)(1,1'-Biphenyl)-4-Yl)Amino)-2'-Deoxy- is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive research applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We adhere to cGMP principles where applicable to support our clients' regulatory and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.