Description

15,23-Dihydrosirohydrochlorin is a key intermediate compound in the biosynthesis of vitamin B12 and related corrinoids. Its precise chemical structure makes it a valuable reference standard and a critical building block for research and development in biochemistry and synthetic biology. This high-purity compound is essential for pharmaceutical R&D, academic research, and the production of specialized biochemical reagents.

Application

• Biochemical Research: Serves as a crucial intermediate in studies of the vitamin B12 (cobalamin) biosynthetic pathway.
• Reference Standard: Used as a high-purity analytical standard for the identification and quantification of related tetrapyrroles in complex matrices.
• Enzymology Studies: Employed as a substrate or precursor to investigate the function of enzymes like sirohydrochlorin cobaltochelatase (CbiX).
• Synthetic Biology: Acts as a precursor molecule in engineered pathways for the microbial production of corrinoids.
• Pharmaceutical Development: Utilized in research focused on novel cobalamin analogs and related therapeutic agents.
• Academic & Industrial R&D: Fundamental material for exploring tetrapyrrole chemistry, catalysis, and cofactor synthesis.

Basic Information

Product Name	15,23-Dihydrosirohydrochlorin
CAS No.	82542-92-5
Molecular Formula	C₄₂H₄₈N₄O₁₆
Molecular Weight	888.85 g/mol
Synonyms	15,23-Dihydro-8,12-diethenyl-2,7,13,17-tetramethyl-3,18-divinylporphyrin-2,17-dipropanoic acid; Sirohydrochlorin (reduced form); Dihydrosirohydrochlorin; Factor II; 15,23-Dihydroisobacteriochlorin; Isobacteriochlorin intermediate; Vitamin B12 biosynthetic intermediate; 8,12-Diethenyl-2,7,13,17-tetramethyl-3,18-divinyl-15,23-dihydroporphyrin-2,17-dipropionic acid
EINECS	Contact for details

Quality Control

Our 15,23-Dihydrosirohydrochlorin is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and degradation. The material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	Dark red to purple solid
Identification (HPLC)	Conforms to reference standard
Identification (UV-Vis)	Conforms to reference spectrum
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 2.0 %
Solubility	Soluble in DMSO, DMF; sparingly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.