Description

1-o-Glucosyl-2-n-(Dimethylaminonaphthalene-5-Sulfonyl)Sphingosine is a sophisticated fluorescently labeled sphingolipid derivative, designed for advanced research applications. This compound is crucial for studying cellular processes involving sphingolipid metabolism, trafficking, and membrane dynamics due to its built-in fluorescent reporter. It is primarily needed by researchers and scientists in the fields of biochemistry, cell biology, and lipidomics for use as a vital molecular probe.

Application

• Fluorescent Labeling Agent: Acts as a critical probe for tracing and visualizing sphingolipids in live-cell imaging and fluorescence microscopy studies.
• Biochemical Research: Used to investigate sphingolipid metabolism, enzyme activity (e.g., glucosylceramide synthase), and intracellular signaling pathways.
• Membrane Biology Studies: Employed to study lipid raft formation, membrane fluidity, and the role of glycosphingolipids in cell membranes.
• Cell Trafficking & Sorting: A valuable tool for tracking the intracellular transport and sorting of glycosphingolipids within the endocytic and secretory pathways.
• Pharmaceutical Development: Serves as a reference standard or investigative tool in drug discovery programs targeting lipid-related diseases.
• Diagnostic Assay Development: Can be utilized in the development of sensitive fluorescence-based assays for detecting enzymatic deficiencies or lipid storage disorders.

Basic Information

Product Name	1-o-Glucosyl-2-n-(Dimethylaminonaphthalene-5-Sulfonyl)Sphingosine
CAS No.	82535-65-7
Molecular Formula	C38H60N2O10S
Molecular Weight	736.96 g/mol
Synonyms	Dansyl-Glucosylceramide; N-[6-[(Dimethylamino)-2-naphthalenyl]sulfonyl]-D-erythro-sphingosine 1-O-β-D-Glucopyranoside; 1-O-(β-D-Glucopyranosyl)-N-[5-(dimethylamino)naphthalene-1-sulfonyl]-D-erythro-sphingosine; D-erythro-Glucosylceramide, N-dansyl-; Fluorescent Glucosylceramide; N-Dansyl-Glucosylceramide; GlcCer-Dansyl; D-erythro-C18-Glucosylceramide, N-[5-(dimethylamino)-1-naphthalenesulfonyl]-
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing key parameters such as purity (by HPLC), identity confirmation (by NMR/MS), and fluorescence properties. We adhere to strict quality management protocols suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, keep the container sealed under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	Yellow to orange solid or film
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95% (Area %)
Solubility	Soluble in DMSO, DMF, Chloroform/Methanol mixtures
Fluorescence Properties	Excitation ~335 nm, Emission ~518 nm (solvent dependent)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.