Description

Monoformyl Gramicidin S is a chemically modified derivative of the classic cyclic decapeptide antibiotic, Gramicidin S. This derivative is valued for its enhanced stability and specific bioactivity profile, making it a crucial intermediate in advanced pharmaceutical research and development. It is primarily utilized by researchers and manufacturers in the life sciences sector for studying antimicrobial mechanisms and developing novel therapeutic agents.

Application

• Pharmaceutical Research: As a key intermediate in the synthesis and study of novel antimicrobial peptide analogs.
• Mechanistic Studies: For investigating the structure-activity relationships (SAR) of peptide antibiotics and their interaction with bacterial membranes.
• Bioconjugation: Serving as a building block for creating peptide-drug conjugates or labeled probes for diagnostic applications.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and validation.
• Biochemical Tool: In microbiological assays to study bacterial resistance and the efficacy of combination therapies.

Basic Information

Item	Detail
Product Name	Monoformyl Gramicidin S
CAS No.	82512-60-5
Molecular Formula	C62H90N12O11
Molecular Weight	1179.45 g/mol
Synonyms	Nα-Formylgramicidin S; Formyl-Gramicidin S; Gramicidin S Monoformyl Derivative; Cyclo(-Val-Orn-Leu-D-Phe-Pro-)2, Nα-Formyl; Gramicidin S, Nα-formyl-; [Formyl1]Gramicidin S
EINECS	Contact for details

Quality Control

Our Monoformyl Gramicidin S is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 2.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.