Description

Ristocetin Sulfate Salt is a glycopeptide antibiotic complex derived from *Amycolatopsis lurida*, primarily recognized for its specific biochemical activity. This compound matters significantly in research and diagnostic applications due to its unique mechanism of binding to the D-Ala-D-Ala terminus of peptidoglycan precursors. It is essential for professionals in pharmaceutical research, clinical diagnostics, and microbiology, particularly for studying bacterial cell wall synthesis and platelet aggregation.

Application

• Pharmaceutical Research: Used as a critical tool in studying the mechanism of action of glycopeptide antibiotics and for the development of novel antimicrobial agents.
• Clinical Diagnostics: Employed in laboratory assays, most notably the ristocetin-induced platelet aggregation (RIPA) test for diagnosing von Willebrand disease and Bernard-Soulier syndrome.
• Microbiological Studies: Serves as a selective agent in research focused on Gram-positive bacteria, particularly for investigating antibiotic resistance mechanisms like Vancomycin-Resistant Enterococci (VRE).
• Biochemical Reagent: Acts as a key reagent in studying protein-carbohydrate interactions and bacterial cell wall biosynthesis pathways.
• Quality Control Reference Standard: Utilized as a reference standard in the pharmaceutical industry for the quality control and potency testing of related antibiotic preparations.

Basic Information

Product Name	Ristocetin Sulfate Salt
CAS No.	1404-55-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Ristocetin Sulfate; Ristocetin A Sulfate; Ristocetin B Sulfate; Ristomycin Sulfate; Spontin; Riston; Antibiotic A 3823; Antibiotic A-3823; Ristocetin Sulfate Complex
EINECS	Contact for details

Quality Control

Our Ristocetin Sulfate Salt is produced and tested under a rigorous quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and potency, meeting the high standards required for research and diagnostic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, purity, and microbiological data.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Assay (HPLC)	≥ 95.0% (on dried basis)
Loss on Drying	≤ 5.0%
pH (1% solution)	4.0 - 6.0
Biological Activity	Conforms to reference

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.