Description

Polymixin-B-Sulfate CAS NO 1406-11-7 is a polypeptide antibiotic complex derived from *Bacillus polymyxa*, widely recognized for its potent bactericidal activity against Gram-negative bacteria. Its primary commercial value lies in its critical role as an active pharmaceutical ingredient (API) in topical and ophthalmic formulations, as well as in veterinary medicine. This product is essential for manufacturers in the pharmaceutical, veterinary pharmaceutical, and research sectors requiring a reliable, high-purity source for antimicrobial applications.

Application

• Active Pharmaceutical Ingredient (API) in topical antibiotic ointments and creams.
• Key component in ophthalmic solutions and drops for treating eye infections.
• Formulation base for veterinary medicinal products targeting Gram-negative infections.
• Research and development of novel antimicrobial agents and combination therapies.
• Use in cell culture media as a selective agent in microbiological laboratories.
• Intermediate in the synthesis of more complex antibiotic derivatives.

Basic Information

Item	Details
Product Name	Polymixin-B-Sulfate
CAS No.	1406-11-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Polymyxin B Sulfate; Aerosporin; Polyfax; Polymyxin B Sulphate; Polymyxin B; Polymixin B; Polimixina B Sulfato
EINECS	Contact for details

Quality Control

Our Polymixin-B-Sulfate is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. Certificates of Analysis (COA) documenting key parameters such as potency, purity, and related substances are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to standard
Assay (Potency)	≥ 6,500 IU/mg
pH (1% Solution)	5.0 - 7.5
Loss on Drying	≤ 7.0 %
Related Substances (HPLC)	Complies with standard limits
Bacterial Endotoxins	< 10.0 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.