Description

Tyrothricin is a polypeptide antibiotic complex primarily composed of gramicidin and tyrocidine, derived from the bacterium *Bacillus brevis*. This compound is valued for its potent antimicrobial activity against a broad spectrum of Gram-positive bacteria. It is a critical raw material for the pharmaceutical and biotechnology industries, particularly in the formulation of topical antiseptics, throat lozenges, and certain veterinary medicinal products. Tyrothricin CAS NO 1404-88-2 is essential for manufacturers requiring a reliable, high-purity antibiotic for therapeutic and research applications.

Application

• Active Pharmaceutical Ingredient (API) in topical antiseptic creams, ointments, and sprays.
• Key component in medicated throat lozenges and oral pastilles for sore throat relief.
• Formulation of veterinary medicinal products for topical infections in animals.
• Use in microbiological research as a selective agent against Gram-positive organisms.
• Potential ingredient in preservative systems for specific cosmetic and personal care formulations.
• Starting material for the synthesis and research of novel antibiotic derivatives.

Basic Information

Product Name	Tyrothricin
CAS No.	1404-88-2
Molecular Formula	Mixture (C~99~H~140~N~20~O~28~ / C~66~H~103~N~17~O~13~)
Molecular Weight	~ 2300 g/mol (Gramicidin) / ~ 1300 g/mol (Tyrocidine)
Synonyms	Tyrothricin; Tyrothrycin; Gramicidin-Tyrocidine Complex; Antibiotic from B. brevis; Faringosept; Biotracin; Tirotricina; Tyroderm
EINECS	215-772-5

Quality Control

Our Tyrothricin is produced and tested under strict quality management systems. Each batch is analyzed to ensure it meets high-purity standards suitable for pharmaceutical applications. We provide comprehensive Certificates of Analysis (COA) detailing key parameters such as potency, related substances, and microbiological quality. The product can be supplied to meet various pharmacopoeial standards, including USP and EP monographs, upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	White to pale yellow powder
Identification (IR)	Conforms to standard
Assay (HPLC)	≥ 95.0% (Total Tyrothricin)
Potency (Microbiological)	≥ 900 Units/mg
Loss on Drying	≤ 5.0 %
Residue on Ignition	≤ 1.0 %
Heavy Metals	≤ 20 ppm
Microbial Limits	Meets Ph. Eur. requirements

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.