Description

Vancomycin Hydrochloride is a glycopeptide antibiotic salt, a critical pharmaceutical active ingredient essential for combating severe Gram-positive bacterial infections. Its primary value lies in its efficacy against methicillin-resistant *Staphylococcus aureus* (MRSA) and other resistant strains, making it a last-line defense in clinical settings. This high-purity compound is vital for manufacturers in the pharmaceutical industry, specifically for the production of sterile injectable formulations and in advanced research for novel antibacterial therapies. The product is identified by CAS NO 1404-93-9.

Application

• Pharmaceutical API Manufacturing: Primary use as the active pharmaceutical ingredient (API) in the production of sterile injectable solutions for hospital use.
• Antibacterial Drug Formulation: Formulation into various dosage forms for the treatment of serious infections like sepsis, endocarditis, and meningitis.
• Clinical & Hospital Pharmacy: Used in hospital compounding for specific patient needs where standard formulations are unsuitable.
• Microbiological Research: Serves as a standard or tool in research laboratories studying antibiotic resistance mechanisms and developing new antibacterial agents.
• Reference Standard: Utilized as a high-purity chemical reference standard in quality control laboratories for analytical method development and validation.
• Veterinary Medicine: Application in veterinary pharmaceuticals for treating serious bacterial infections in animals.

Basic Information

Product Name	Vancomycin Hydrochloride
CAS No.	1404-93-9
Molecular Formula	C66H75Cl2N9O24 · HCl
Molecular Weight	Approx. 1485.7 g/mol
Synonyms	Vancomycin HCl; Vancocin Hydrochloride; Vancomycin Monohydrochloride; (1S,2R,18R,19R,22S,25R,28R,40S)-48-{[(2S,3R,4S,5S,6R)-4-Amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-22-(carbamoylmethyl)-5,15-dichloro-2,18,32,35,37-pentahydroxy-19-{[(2R)-4-methyl-2-(methylamino)pentanamido]methyl}-20,23,26,42,44-pentaoxo-7,13-dioxa-21,24,27,41,43-pentaazaoctacyclo[26.14.2.2³,⁶.2¹⁴,¹⁷.1⁸,¹².1²⁹,³³.0¹⁰,²⁵.0³⁴,³⁹]pentaconta-3,5,8(48),9,11,14,16,29(45),30,32,34,36,46,49-tetradecaene-40-carboxylic acid hydrochloride
EINECS	215-772-6

Quality Control

Our Vancomycin Hydrochloride is manufactured and tested under strict quality management systems. It is suitable for use as a pharmaceutical intermediate or API, with testing protocols designed to meet relevant industry standards. A comprehensive Certificate of Analysis (COA) is provided with each batch, detailing key parameters such as purity, potency, and impurity profiles to ensure consistency and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	≥ 95.0% (on anhydrous basis)
Potency	≥ 900 µg/mg
pH (1% solution)	2.5 - 4.5
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 5.0%
Bacterial Endotoxins	< 0.25 EU/mg (for applicable grades)
Sterility	Conforms (for sterile grades)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.