Description

Colistina [Inn-Spanish] is a polypeptide antibiotic belonging to the polymyxin class, known for its potent activity against Gram-negative bacteria. This compound is critical for addressing serious infections, particularly those caused by multidrug-resistant pathogens. It is primarily utilized in the pharmaceutical and veterinary sectors for the formulation of injectable and topical medications.

Application

• Pharmaceutical Active Ingredient (API): Used in the manufacture of injectable antibiotics for systemic infections.
• Veterinary Medicine: Formulated into treatments for bacterial infections in livestock and companion animals.
• Topical Preparations: Incorporated into ointments, creams, and powders for skin and wound infections.
• Research & Development: Serves as a reference standard and key reagent in microbiological and pharmacological studies.
• Combination Therapies: Used in synergistic formulations with other antibiotics to combat resistance.

Basic Information

Product Name	Colistina [Inn-Spanish]
CAS No.	1404-31-5
Molecular Formula	C52H98N16O13
Molecular Weight	1155.43 g/mol
Synonyms	Colistin; Polymyxin E; Colimycin; Coly-Mycin; Colistin Sulfate; Colistimethate Sodium; Colistina; [1-[[4-[[3,11-Diamino-8-[1-[[(2S)-5-diaminomethyl-1-oxidanylidene-2-pentanyl]amino]-8-azanyl-2-oxidanylidene-6,9,12,15-tetraoxa-3,10-diazabicyclo[13.3.1]nonadeca-1(19),16,17-trien-7-yl]amino]-1,4-dioxobutyl]amino]-3-azanyl-1-oxobutyl]amino]-3-hydroxy-1-oxobutan-2-yl]-6-methyloctanamide
EINECS	215-777-6

Quality Control

Our Colistina [Inn-Spanish] is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and potency, to ensure compliance with pharmaceutical-grade standards. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and microbiological quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a low-humidity environment to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm
Bacterial Endotoxins	< 0.5 EU/mg
Microbial Enumeration	Conforms to EP/USP

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.