Description

Dolichyl Palmitate is a high-purity ester compound formed from dolichol and palmitic acid, serving as a critical biochemical intermediate. Its primary value lies in its role as a precursor in the biosynthesis of N-linked glycoproteins, a fundamental process in cellular biology and protein function. This makes it an essential material for research and development in the life sciences, particularly for pharmaceutical companies and academic institutions studying glycosylation pathways, membrane protein synthesis, and related metabolic disorders.

Application

• Biochemical Research: A key substrate and intermediate in the study of N-linked protein glycosylation, a vital post-translational modification.
• Pharmaceutical Development: Used in R&D for investigating metabolic diseases related to dolichol and glycosylation pathways, such as certain congenital disorders of glycosylation (CDGs).
• Enzymology Studies: Serves as a standard or substrate for assays involving enzymes like dolichyl-phosphate mannosyltransferase and other glycosyltransferases.
• Reference Standard: Employed as a high-purity analytical standard in chromatography (HPLC, GC) and mass spectrometry for qualitative and quantitative analysis.
• Cell Culture & In-vitro Studies: Potentially used in specialized cell culture media or in-vitro systems to study lipid metabolism and membrane biogenesis.
• Cosmetic Science (High-Grade): In premium formulations, it may be explored for its skin-conditioning and emollient properties, given its lipid-like structure.

Basic Information

Product Name	Dolichyl Palmitate
CAS No.	82446-32-0
Molecular Formula	Typically C91H162O2 (for Dolichol-16 with C16 palmitate; varies with dolichol chain length)
Molecular Weight	Contact for details (varies with specific dolichol homolog)
Synonyms	Dolichol Palmitate; Dolichol Hexadecanoate; (all-E)-3,7,11,15,19,23,27,31,35,39,43,47,51,55,59,63-Hexadecamethylhexaconta-2,6,10,14,18,22,26,30,34,38,42,46,50,54,58,62-hexadecaen-1-yl Hexadecanoate; Hexadecanoic Acid (all-E)-3,7,11,15,19,23,27,31,35,39,43,47,51,55,59,63-Hexadecamethylhexaconta-2,6,10,14,18,22,26,30,34,38,42,46,50,54,58,62-hexadecaen-1-yl Ester; Polyprenyl Palmitate
EINECS	Contact for details

Quality Control

Our Dolichyl Palmitate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We can supply material that meets the stringent requirements for use as a reference standard or biochemical reagent.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) or as specified on the label. This product is light-sensitive and easily oxidized; prolonged exposure to air, light, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white waxy solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95% (Area %)
Purity (TLC)	Single major spot
Solubility	Soluble in chloroform, DMSO; slightly soluble in ethanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.