Description

1H-Indole, 4-(1-Ethyl-3-Piperidinyl)-, (E)-2-Butenedioate (2:1) is a high-purity, non-racemic organic salt of significant interest in advanced chemical synthesis. This compound matters as a critical chiral intermediate or building block for the development of complex, biologically active molecules. Pharmaceutical research and fine chemical manufacturers need it for the production of specialized APIs and novel chemical entities, where precise stereochemistry and reliable quality are paramount.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of potential Active Pharmaceutical Ingredients (APIs), particularly for central nervous system (CNS) or receptor-targeted therapies.
• Asymmetric Synthesis: Utilized in catalytic or stoichiometric reactions where its specific indole-piperidine structure introduces desired stereochemical complexity.
• Medicinal Chemistry Research: Employed in drug discovery programs for constructing compound libraries and exploring structure-activity relationships (SAR).
• Fine Chemical Production: Acts as a precursor for manufacturing specialty chemicals, agrochemicals, or advanced materials requiring high-purity intermediates.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	1H-Indole, 4-(1-Ethyl-3-Piperidinyl)-, (E)-2-Butenedioate (2:1)
CAS No.	82439-15-4
Molecular Formula	C15H20N2 • 0.5C4H4O4
Molecular Weight	Contact for details
Synonyms	4-(1-Ethyl-3-piperidinyl)-1H-indole fumarate (2:1 salt); (E)-2-Butenedioic acid, compd. with 4-(1-ethyl-3-piperidinyl)-1H-indole (2:1); 4-(1-Ethylpiperidin-3-yl)-1H-indole fumarate; Fumaric acid salt of 4-(1-Ethyl-3-piperidinyl)indole; 82439-15-4; UNII-8Q3TQY9C9F
EINECS	Contact for details

Quality Control

Our 1H-Indole, 4-(1-Ethyl-3-Piperidinyl)-, (E)-2-Butenedioate (2:1) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment, to ensure it meets the high standards required for pharmaceutical research and fine chemical synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.