Description

Dmt-Thymidine 2-Clph Diester Barium) is a specialized, organometallic nucleotide derivative used as a critical building block in advanced organic synthesis. This compound matters for its role in facilitating precise chemical modifications, particularly in the synthesis of complex nucleoside analogs and oligonucleotides. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, diagnostic probes, and high-value fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of modified nucleosides and nucleotides for antiviral and anticancer drug candidates.
• Oligonucleotide Synthesis: Used in the preparation of protected phosphoramidite monomers for solid-phase DNA/RNA synthesis.
• Bioconjugation Chemistry: Serves as a versatile linker or modifier for attaching labels or functional groups to biomolecules.
• Chemical Biology Research: Employed in the study of nucleic acid structure, function, and enzyme interactions.
• Fine Chemical Production: Acts as a specialized reagent for the custom synthesis of high-purity, complex organic molecules.

Basic Information

Product Name	Dmt-Thymidine 2-Clph Diester Barium)
CAS No.	82225-23-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	5'-O-(4,4'-Dimethoxytrityl)thymidine 3'-(2-chlorophenyl) phosphate barium salt; DMT-Thymidine-3'-(2-ClPh) Barium Salt; Thymidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-(2-chlorophenyl) hydrogen phosphate, barium salt; Barium 5'-O-DMT-thymidine-3'-(2-chlorophenyl) phosphate; DMT-dT(2-ClPh) Barium Salt; Nucleoside Phosphotriester Barium Salt; 82225-23-8
EINECS	Contact for details

Quality Control

Our Dmt-Thymidine 2-Clph Diester Barium) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. Handle and store under an inert atmosphere such as argon or nitrogen for long-term stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Barium Content	Conforms to theoretical

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.