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Succinyl-Alanyl-Tyrosyl-Leucyl-Valyl-4-Nitroanilide CAS NO 82155-66-6


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CAS No.:82155-66-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Succinyl-Alanyl-Tyrosyl-Leucyl-Valyl-4-Nitroanilide is a synthetic peptide substrate designed for enzymatic activity assays. This compound matters for its high specificity and sensitivity in biochemical research, particularly for studying protease and peptidase kinetics. It is primarily needed by pharmaceutical R&D laboratories, diagnostic kit manufacturers, and academic institutions conducting proteolytic enzyme research.

Application

  • Protease/Peptidase Substrate: A chromogenic substrate for the kinetic study and characterization of various serine and cysteine proteases.
  • Enzyme Inhibition Assays: Used in high-throughput screening (HTS) to identify and evaluate potential protease inhibitor drug candidates.
  • Diagnostic Reagent Manufacturing: A key component in the formulation of diagnostic kits for clinical analysis of specific enzyme levels.
  • Biochemical Research: Employed in academic and industrial laboratories to investigate enzyme mechanisms, substrate specificity, and catalytic efficiency.
  • Quality Control in Biologics: Used to monitor and quantify protease activity during the production and purification of biopharmaceuticals.

Basic Information

Product Name Succinyl-Alanyl-Tyrosyl-Leucyl-Valyl-4-Nitroanilide
CAS No. 82155-66-6
Molecular Formula C34H46N8O11
Molecular Weight 742.78 g/mol
Synonyms Suc-Ala-Tyr-Leu-Val-pNA; Suc-A-Y-L-V-pNA; Succinyl-Ala-Tyr-Leu-Val-4-Nitroanilide; 4-Nitroanilide, N-succinyl-L-alanyl-L-tyrosyl-L-leucyl-L-valyl-; Protease Substrate Suc-A-Y-L-V-pNA; Chromogenic Peptide Substrate 82155-66-6; N-Succinyl-L-Alanyl-L-Tyrosyl-L-Leucyl-L-Valyl-4-Nitroanilide
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Quality Control

Our Succinyl-Alanyl-Tyrosyl-Leucyl-Valyl-4-Nitroanilide is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot undergoes comprehensive analytical testing including HPLC for purity, identity confirmation (IR, MS), and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and should be allowed to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC) Conforms to reference standard
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 5.0%
Solubility Soluble in DMSO, DMF; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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