Description

L-Aspartic Acid, n-(4-(((2,4-Diamino-7-Pteridinyl)Methyl)Methylamino)Benzoyl)- is a specialized folate derivative and a key biochemical intermediate. This compound is critical for research and development in the life sciences, particularly in the study of enzyme inhibition and metabolic pathways. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of high-purity biochemical reagents.

Application

• Pharmaceutical Research & Development: Serves as a crucial intermediate in the synthesis and study of novel antifolate drugs and enzyme inhibitors.
• Biochemical Assay Development: Used as a reference standard or active component in enzymatic and cellular assays targeting folate-dependent processes.
• Academic & Life Science Research: A vital tool for investigating one-carbon metabolism, nucleotide biosynthesis, and related biochemical pathways in experimental models.
• High-Purity Reference Material: Supplied as a certified reference standard for analytical method development and quality control in pharmaceutical analysis.
• Precursor for Specialty Chemicals: Acts as a building block for the synthesis of more complex, targeted biochemical modulators and probes.

Basic Information

Product Name	L-Aspartic Acid, n-(4-(((2,4-Diamino-7-Pteridinyl)Methyl)Methylamino)Benzoyl)-
CAS No.	82144-21-6
Molecular Formula	C23H24N8O5
Molecular Weight	492.49 g/mol
Synonyms	N-[4-[[(2,4-Diamino-7H-pteridin-6-yl)methyl]methylamino]benzoyl]-L-aspartic acid; Methotrexate-α-aspartic acid; MTX-Asp; MTX-α-Asp; L-Aspartic acid, N-[4-[[(2,4-diamino-7H-pteridin-6-yl)methyl]methylamino]benzoyl]-; 4-[[(2,4-Diaminopteridin-6-yl)methyl]methylamino]benzoic acid L-aspartic acid conjugate; Folate-Aspartic Acid Conjugate
EINECS	Contact for details

Quality Control

Our production of L-Aspartic Acid, n-(4-(((2,4-Diamino-7-Pteridinyl)Methyl)Methylamino)Benzoyl)- adheres to stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets exacting research-grade specifications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance with your research protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (HPLC/UV)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.