Description

1,3-Didecanoyl-2-(6-(5-Fluorouracil-1-Yl)Carbonylamino)Glyceride is a specialized synthetic glyceride derivative designed for advanced pharmaceutical and biochemical research. This compound is engineered to act as a prodrug or a targeted delivery vehicle, leveraging the therapeutic potential of the 5-fluorouracil moiety for enhanced efficacy and reduced systemic toxicity. It is primarily utilized by researchers and developers in the pharmaceutical industry, particularly those focused on oncology drug development, prodrug strategies, and novel lipid-based delivery systems.

Application

• Oncology Research & Drug Development: Serves as a key intermediate or active pharmaceutical ingredient (API) in the synthesis of novel chemotherapeutic prodrugs targeting cancer cells.
• Lipid-Based Drug Delivery Systems: Incorporated into liposomes, nanoparticles, or other lipid formulations to improve the solubility, stability, and targeted delivery of 5-fluorouracil and related compounds.
• Biochemical Probes & Molecular Biology: Used in research to study enzyme activity, cellular uptake mechanisms, and metabolic pathways involving nucleoside analogs.
• Pharmaceutical Intermediates: Acts as a critical building block for the synthesis of more complex, therapeutically active molecules in medicinal chemistry.
• Controlled-Release Formulations: Explored for developing sustained-release drug delivery platforms due to its glyceride backbone, which can be tailored for specific release profiles.

Basic Information

Product Name	1,3-Didecanoyl-2-(6-(5-Fluorouracil-1-Yl)Carbonylamino)Glyceride
CAS No.	81821-86-5
Molecular Formula	C29H46FN3O7
Molecular Weight	567.70 g/mol
Synonyms	1,3-Didecanoyl-2-[(6-((5-fluoro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)carbonyl)amino)hexanoyl]glycerol; 5-FU Glyceride Derivative; 2-[(6-((5-Fluoro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)carbonyl)amino)hexanoyl]-1,3-didecanoylglycerol; N-(6-((5-Fluoro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)carbonyl)amino)hexanoyl)-1,3-didecanoylglycerol; Fluorouracil Glyceride Conjugate; 1,3-Dicaprinoyl-2-(6-(5-fluorouracil-1-yl)carbonylamino)hexanoylglycerol
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and pharmaceutical development. Each batch is characterized using advanced analytical techniques to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity, related substances, and other critical parameters are available upon request. We adhere to strict quality management principles to support your regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.