Description

Swainsonine n-Oxide is a chemically modified derivative of the indolizidine alkaloid swainsonine, characterized by the oxidation of its nitrogen atom. This compound is of significant interest in biochemical and pharmacological research due to its role as a potential modulator of glycosidase enzyme activity. It serves as a critical reference standard and intermediate for researchers and developers in the life sciences sector, particularly for investigating enzyme inhibition pathways and developing novel therapeutic agents.

Application

• Biochemical Research: Used as a high-purity reference standard in studies of α-mannosidase and other glycosidase enzymes.
• Pharmaceutical Development: Acts as a key intermediate or building block in the synthesis of potential drug candidates targeting lysosomal storage disorders.
• Metabolic Pathway Analysis: Employed in cell-based assays to study the effects of glycosidase inhibition on glycoprotein processing and cellular metabolism.
• Academic Research: Utilized in universities and research institutes for fundamental studies in organic chemistry, medicinal chemistry, and chemical biology.
• Quality Control: Serves as an analytical standard for the identification and quantification of swainsonine-related compounds in raw materials or finished products.

Basic Information

Product Name	Swainsonine n-Oxide
CAS No.	81759-44-6
Molecular Formula	C8H15NO4
Molecular Weight	189.21 g/mol
Synonyms	(1S,2R,8R,8aR)-1,2,8-Trihydroxyoctahydroindolizidin-8-ium-8-olate; Swainsonine N-Oxide; Swainsonine Oxide; 8-Hydroxyswainsonine; Indolizidine-1,2,8-triol, 8-oxide (1S,2R,8R,8aR)-
EINECS	Contact for details

Quality Control

Our Swainsonine n-Oxide is produced under a rigorous quality management system. Each batch is subjected to comprehensive analytical testing, including HPLC for purity determination and spectroscopic methods (NMR, MS) for structural confirmation, to ensure it meets the high standards required for research applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.