Description

S-Nitroso-N-Acetyl-DL-Penicillamine (SNAP) is a stable, cell-permeable nitric oxide (NO) donor compound widely used in biochemical research. Its primary value lies in its ability to reliably and controllably release nitric oxide, a critical signaling molecule, under physiological conditions. This makes it an essential research tool for scientists and pharmaceutical developers studying NO-mediated processes, including vasodilation, neurotransmission, and immune response.

Application

• Biochemical Research: As a standard nitric oxide donor for studying the role of NO in cellular signaling pathways, apoptosis, and gene expression.
• Cardiovascular Research: Investigation of vasodilation, blood pressure regulation, and endothelial function in experimental models.
• Neuroscience: Research into NO's function as a neurotransmitter and neuromodulator, including studies on synaptic plasticity and neuroprotection.
• Immunology & Inflammation Studies: Exploring the antimicrobial and immunomodulatory actions of nitric oxide in macrophage and other immune cell responses.
• Pharmaceutical Development: Used as a reference compound and tool in the preclinical development of therapies targeting NO pathways.
• Cell Culture & In Vitro Assays: Providing a controlled source of NO to examine its effects on cell proliferation, differentiation, and cytotoxicity.

Basic Information

Product Name	S-Nitroso-N-Acetyl-DL-Penicillamine
CAS No.	81739-40-4
Molecular Formula	C7H12N2O4S
Molecular Weight	220.25 g/mol
Synonyms	SNAP; S-Nitroso-N-acetylpenicillamine; N-Acetyl-S-nitroso-DL-penicillamine; S-Nitroso-N-acetyl-DL-penicillamine; Nitric Oxide Donor SNAP; (2R)-2-Acetamido-3-methyl-3-(nitrososulfanyl)butanoic acid; (2S)-2-Acetamido-3-methyl-3-(nitrososulfanyl)butanoic acid
EINECS	Contact for details

Quality Control

Our S-Nitroso-N-Acetyl-DL-Penicillamine is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and stability data. We adhere to relevant quality standards for research chemicals to guarantee reliable and reproducible experimental results.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and degradation. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	Green crystalline solid or powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.