Description

1,2-Propanediamine, 3-(4-Nitrophenyl)-, (2S)- is a chiral, nitro-substituted diamine building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and sophisticated chiral ligands. Pharmaceutical researchers and fine chemical manufacturers need it to create molecules with specific three-dimensional configurations, which are critical for biological activity and material properties. Its defined stereochemistry and functional groups make it a valuable precursor for complex chemical transformations.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel Active Pharmaceutical Ingredients (APIs), particularly in therapeutic areas requiring high stereochemical purity.
• Catalyst & Ligand Synthesis: Used in the preparation of chiral ligands and organocatalysts for asymmetric synthesis, enabling more efficient and selective chemical reactions.
• Agrochemical Research: Serves as a precursor in the development of advanced, chiral agrochemicals such as herbicides and fungicides.
• Material Science: Employed in the synthesis of specialty polymers, dyes, and advanced organic materials where the nitro and amine functionalities are utilized.
• Academic & R&D: A valuable reagent for research in organic chemistry, medicinal chemistry, and process development within university and industrial laboratories.

Basic Information

Product Name	1,2-Propanediamine, 3-(4-Nitrophenyl)-, (2S)-
CAS No.	81677-62-5
Molecular Formula	C9H13N3O2
Molecular Weight	195.22 g/mol
Synonyms	(2S)-3-(4-Nitrophenyl)-1,2-propanediamine; (S)-3-(4-Nitrophenyl)-1,2-propanediamine; (S)-3-(4-Nitrophenyl)propane-1,2-diamine; 1,2-Diamino-3-(4-nitrophenyl)propane, (S)-; L-3-(4-Nitrophenyl)-1,2-diaminopropane; (S)-1,2-Diamino-3-(4-nitrophenyl)propane; 3-(p-Nitrophenyl)-(S)-1,2-propanediamine; (2S)-3-(4-Nitrophenyl)propane-1,2-diamine
EINECS	Contact for details

Quality Control

Our production of 1,2-Propanediamine, 3-(4-Nitrophenyl)-, (2S)- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The material is characterized using advanced analytical techniques including HPLC, GC, and chiral analysis to confirm identity, purity, and enantiomeric excess. Certificates of Analysis (COA) detailing all relevant specifications are provided with each shipment. We support cGMP compliance for pharmaceutical applications and can tailor quality documentation to meet specific customer and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, containers should be kept tightly sealed to exclude moisture. Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.