Description

Arazide 5'-Triphosphate is a chemically modified nucleotide analog, specifically an azide-functionalized derivative of adenosine triphosphate (ATP). This compound is a critical reagent in bioorthogonal chemistry and click chemistry applications, enabling selective labeling and conjugation of biomolecules. It is essential for researchers and manufacturers in the fields of proteomics, nucleic acid research, chemical biology, and diagnostic assay development, where precise tagging and detection of biological targets are required.

Application

• Bioorthogonal Labeling: Used in Cu-free click chemistry reactions for the site-specific labeling of proteins, nucleic acids, and other biomolecules.
• Proteomics Research: Enables the identification and study of post-translational modifications, protein-protein interactions, and enzyme activity through metabolic incorporation and subsequent conjugation.
• Nucleic Acid Modification: Serves as a substrate for polymerases to incorporate azide tags into DNA or RNA strands for sequencing, detection, or pull-down assays.
• Diagnostic Development: Utilized in the creation of sensitive detection platforms, such as ELISA and lateral flow assays, by conjugating detection probes (e.g., fluorophores, biotin) to target molecules.
• Chemical Biology Probes: Acts as a key building block for synthesizing activity-based probes to profile enzyme function and discover new drug targets.
• Material Science: Facilitates the surface functionalization of nanomaterials and polymers for biomedical and biosensing applications.

Basic Information

Product Name	Arazide 5'-Triphosphate
CAS No.	81542-87-2
Molecular Formula	C10H13N6O12P3
Molecular Weight	502.13 g/mol
Synonyms	8-Azidoadenosine 5'-triphosphate; 8-N3-ATP; 8-Azido-ATP; Azido-ATP; 8-Azidoadenosine triphosphate; Adenosine 5'-triphosphate, 8-azido-; 8-Azido-adenosine-5'-triphosphate
EINECS	Contact for details

Quality Control

Our Arazide 5'-Triphosphate is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 3.0%
Biological Activity	Functional in standard enzymatic assays

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.