Description

1-(2'-Tetrahydrothienyl)-5 Fluorouracil-1-'1'-Dioxide is a specialized fluorinated pyrimidine derivative, a key intermediate in advanced pharmaceutical synthesis. This compound matters for its role in developing novel therapeutic agents, particularly in oncology and antiviral research, where precise molecular architecture is critical. It is needed by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers focused on creating next-generation active pharmaceutical ingredients (APIs).

Application

• Primary intermediate in the synthesis of novel chemotherapeutic agents and targeted cancer therapies.
• Key building block for research into fluorouracil prodrugs with enhanced bioavailability and reduced side effects.
• Used in the development of antiviral compounds, leveraging its modified nucleobase structure.
• Precursor in medicinal chemistry research for structure-activity relationship (SAR) studies.
• Employed in academic and industrial R&D for exploring new mechanisms of action in cell proliferation inhibition.
• Starting material for the preparation of radiolabeled compounds for diagnostic and pharmacokinetic studies.

Basic Information

Product Name	1-(2'-Tetrahydrothienyl)-5 Fluorouracil-1-'1'-Dioxide
CAS No.	81486-02-4
Molecular Formula	C9H9FN2O3S
Molecular Weight	244.24 g/mol
Synonyms	1-(Tetrahydro-2-thienyl)-5-fluorouracil 1,1-dioxide; 5-Fluoro-1-(tetrahydro-2-thienyl)uracil 1,1-dioxide; 1-(Tetrahydrothiophen-2-yl)-5-fluoropyrimidine-2,4(1H,3H)-dione 1,1-dioxide; FT-207 derivative; Tegafur intermediate; 5-FU prodrug intermediate; 1-(2-Thienyl)-5-fluorouracil dioxide (tetrahydro); N1-(Tetrahydro-2-thienyl)-5-fluorouracil S,S-dioxide
EINECS	Contact for details

Quality Control

Our 1-(2'-Tetrahydrothienyl)-5 Fluorouracil-1-'1'-Dioxide is produced under a strict quality management system to ensure batch-to-batch consistency and high purity, suitable for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.